Rabbit polyclonal AIF1 antibody (A1527)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal AIF1 antibody (A1527)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal AIF1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

IBA1 antibody, IRT1 antibody, AIF-1 antibody, IRT-1 antibody
AIF 1 antibody|AIF-1 antibody|Aif1 antibody|AIF1 protein antibody|AIF1_HUMAN antibody|Allograft inflammatory factor 1 antibody|Allograft inflammatory factor 1 splice variant G antibody|allograft inflammatory factor-1 splice variant Hara-1 antibody|balloon angioplasty responsive transcription antibody|BART 1 antibody|G1 antibody|G1 putative splice variant of allograft inflamatory factor 1 antibody|IBA 1 antibody|IBA1 antibody|interferon gamma responsive transcript antibody|Interferon responsive transcript 1 antibody|interferon responsive transcript factor 1 antibody|Ionized calcium binding adapter molecule 1 antibody|Ionized calcium-binding adapter molecule 1 antibody|ionized calcium-binding adapter molecule antibody|IRT 1 antibody|IRT1 antibody|Microglia response factor antibody|MRF1 antibody|Protein g1 antibody|Anti-Iba1 antibody (ab5076)

SCBT cat No: sc-32725|sc-28530|sc-398406|sc-28528|

Name

Rabbit polyclonal AIF1 antibody

Catalogue No.

A1527

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human AIF1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:100 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 17kDa/Observed: Refer to Figures

Formulation

AIF1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

AIF1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

IBA1 antibody, IRT1 antibody, AIF-1 antibody, IRT-1 antibody

Database links

Human UniProt/Swiss-Prot:P55008

Protein names

IBA1, IRT1, AIF-1, IRT-1

Protein function

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Protein tissue specificity

Detected in T-lymphocytes and peripheral blood mononuclear cells.

Protein sequence and domain

Contains 2 EF-hand domains.

Protein post-translational modifications

Phosphorylated on serine residues.

Protein cellular localization

Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Note: Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.

Background

This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Note

AntibodyPlus can customize AIF1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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