Rabbit polyclonal AK1 antibody (A1218)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal AK1 antibody (A1218)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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AK1 antibody
Adenylate kinase 1 antibody|Adenylate kinase isoenzyme 1 antibody|Adenylate kinase soluble antibody|AK 1 antibody|Ak1 antibody|ATP AMP transphosphorylase antibody|ATP-AMP transphosphorylase 1 antibody|KAD1 antibody|KAD1_HUMAN antibody|Myokinase antibody|Anti-Adenylate Kinase 1 antibody (ab54824)

SCBT cat No: sc-365316|sc-165981|sc-365048|sc-28785|

Name

Rabbit polyclonal AK1 antibody

Catalogue No.

A1218

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human AK1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 22kDa/Observed: Refer to Figures

Formulation

AK1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

AK1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

AK1 antibody

Database links

Human UniProt/Swiss-Prot:P00568

Protein names

AK1

Protein function

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.

Protein sequence and domain

Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.Belongs to the adenylate kinase family. AK1 subfamily.

Protein cellular localization

Cytoplasm.

Background

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008]

Research area

All research areas>Kinases and Phosphatases>Adenylate Kinase
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize AK1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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