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Rabbit polyclonal AK1 antibody (A1218)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal AK1 antibody (A1218)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Image descriptions:
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Alternative names:
Check alternative names for the antibody
ExpandAK1 antibody
Adenylate kinase 1 antibody|Adenylate kinase isoenzyme 1 antibody|Adenylate kinase soluble antibody|AK 1 antibody|Ak1 antibody|ATP AMP transphosphorylase antibody|ATP-AMP transphosphorylase 1 antibody|KAD1 antibody|KAD1_HUMAN antibody|Myokinase antibody|Anti-Adenylate Kinase 1 antibody (ab54824)
SCBT cat No: sc-365316|sc-165981|sc-365048|sc-28785|
| Name | Rabbit polyclonal AK1 antibody |
|---|---|
| Catalogue No. | A1218 |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human AK1 |
| Host | Rabbit |
| Applications | WB, IHC, IF |
| Recommended dilution | WB 1:500 – 1:2000 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Molecular weight | Predicted: 22kDa/Observed: Refer to Figures |
| Formulation | AK1 antibody was tube-contained. |
| Purification | AK1 antibody was purified using affinity purification. |
| Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
| Alternative antibody names | AK1 antibody |
| Database links | Human UniProt/Swiss-Prot:P00568 |
| Protein names | AK1 |
| Protein function | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. |
| Protein sequence and domain | Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.Belongs to the adenylate kinase family. AK1 subfamily. |
| Protein cellular localization | Cytoplasm. |
| Background | Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008] |
| Research area | All research areas>Kinases and Phosphatases>Adenylate Kinase |
| Note | AntibodyPlus can customize AK1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
| Product type | Primary antibody |
| Supplier | ABclonal Inc. |
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