Rabbit polyclonal AK4 antibody (A2050)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal AK4 antibody (A2050)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

AK3 antibody, AK3L1 antibody, AK3L2 antibody
Adenylate kinase 3 like 1 antibody|Adenylate kinase 3-like antibody|adenylate kinase 4 antibody|Adenylate kinase isoenzyme 4, mitochondrial antibody|AK3 antibody|AK3L1 antibody|AK3L2 antibody|AK4 antibody|ATP-AMP transphosphorylase antibody|GTP:AMP phosphotransferase antibody|KAD4_HUMAN antibody|MGC166959 antibody|mitochondrial adenylate kinase 3 antibody|nucleoside-triphosphate adenylate kinase antibody|Anti-AK3L1 antibody [EPR7678] (ab131327)

SCBT cat No: sc-53912|sc-271161|sc-398661|sc-366012|sc-17627|

Name

Rabbit polyclonal AK4 antibody

Catalogue No.

A2050

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human AK4

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 25kDa/Observed: Refer to Figures

Formulation

AK4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

AK4 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

AK3 antibody, AK3L1 antibody, AK3L2 antibody

Database links

Human UniProt/Swiss-Prot:P27144

Protein names

AK3, AK3L1, AK3L2

Protein function

Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.

Protein tissue specificity

Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain.

Protein sequence and domain

Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.Belongs to the adenylate kinase family. AK3 subfamily.

Protein cellular localization

Mitochondrion matrix .

Background

This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008]

Research area

All research areas>Kinases and Phosphatases>Adenylate Kinase
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize AK4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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