Rabbit polyclonal AKR7A2 antibody (A1227)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal AKR7A2 antibody (A1227)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal AKR7A2 antibody.

Alternative names:

Check alternative names for the antibody

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AKR7A2 antibody,AFAR antibody,AFAR1 antibody,AFB1-AR1 antibody,AKR7 antibody
AFAR antibody|AFAR1 antibody|AFB1 aldehyde reductase 1 antibody|AFB1 AR1 antibody|AFB1-AR 1 antibody|AFB1AR1 antibody|Aflatoxin aldehyde reductase antibody|Aflatoxin B1 aldehyde reductase member 2 antibody|Aflatoxin beta1 aldehyde reductase antibody|Aiar antibody|AKR7 antibody|Akr7a2 antibody|Aldo keto reductase family 7 antibody|Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase antibody|Aldo keto reductase family 7 member A2 antibody|Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase) antibody|Aldoketoreductase 7 antibody|ARK72_HUMAN antibody|SSA reductase antibody|Succinic semialdehyde reductase antibody|Anti-AKR7A2 antibody (ab175295)

SCBT cat No: sc-66016|sc-80464|sc-130302|sc-69857|sc-51506|sc-8108|

Name

Rabbit polyclonal AKR7A2 antibody

Catalogue No.

A1227

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human AKR7A2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 40kDa/Observed: Refer to Figures

Formulation

AKR7A2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

AKR7A2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

AKR7A2 antibody,AFAR antibody,AFAR1 antibody,AFB1-AR1 antibody,AKR7 antibody

Database links

Human UniProt/Swiss-Prot:O43488

Protein names

AKR7A2,AFAR,AFAR1,AFB1-AR1,AKR7

Protein function

Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Protein tissue specificity

Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen. Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman’s capsules and some cysts. Detected at low levels in lung and pancreas (at protein level). Widely expressed.

Protein sequence and domain

Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.

Protein cellular localization

Golgi apparatus . Cytoplasm .

Background

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. [provided by RefSeq, Oct 2011]

Note

AntibodyPlus can customize AKR7A2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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