Rabbit polyclonal ALDH4A1 antibody (A2595)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ALDH4A1 antibody (A2595)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ALDH4A1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

P5CD antibody, ALDH4 antibody, P5CDh antibody
AL4A1_HUMAN antibody|aldehyde dehydrogenase 4 antibody|aldehyde dehydrogenase 4 family, member A1 antibody|Aldehyde dehydrogenase family 4 member A1 antibody|Aldehyde dehydrogenase, family 4, subfamily A, member 1 antibody|ALDH4 antibody|aldh4a1 antibody|Delta 1 pyrroline 5 carboxylate dehydrogenase, mitochondrial antibody|Delta-1-pyrroline-5-carboxylate dehydrogenase antibody|L-glutamate gamma-semialdehyde dehydrogenase antibody|mitochondrial antibody|mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase antibody|P5C dehydrogenase antibody|P5CD antibody|P5CDh antibody|P5CDhL antibody|P5CDhS antibody|Pyrroline-5-carboxylate dehydrogenase antibody|RP11 128M10.1 antibody|Anti-ALDH4A1 antibody [EPR14287] (ab185208)

SCBT cat No: sc-100499|sc-393354|sc-393339|sc-398911|sc-367309|sc-398894|

Name

Rabbit polyclonal ALDH4A1 antibody

Catalogue No.

A2595

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ALDH4A1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 62kDa/Observed: Refer to Figures

Formulation

ALDH4A1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ALDH4A1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

P5CD antibody, ALDH4 antibody, P5CDh antibody

Database links

Human UniProt/Swiss-Prot:P30038

Protein names

P5CD, ALDH4, P5CDh

Protein function

Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes.

Protein tissue specificity

Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas.

Protein sequence and domain

Belongs to the aldehyde dehydrogenase family.

Protein cellular localization

Mitochondrion matrix.

Background

This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Research area

All research areas>Synthesis and Degradation>ALDH
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize ALDH4A1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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