Rabbit polyclonal ALDH7A1 antibody (A8629)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ALDH7A1 antibody (A8629)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:4000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ALDH7A1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

EPD antibody, PDE antibody, ATQ1 antibody
26g turgor protein homolog antibody|AL7A1_HUMAN antibody|Aldehyde dehydrogenase 7 A1 antibody|Aldehyde dehydrogenase 7 family, member A1 antibody|Aldehyde dehydrogenase family 7 member A1 antibody|ALDH7A1 antibody|Alpha AASA dehydrogenase antibody|Alpha aminoadipic semialdehyde dehydrogenase antibody|Alpha-AASA dehydrogenase antibody|Alpha-aminoadipic semialdehyde dehydrogenase antibody|Antiquitin 1 antibody|Antiquitin antibody|Antiquitin-1 antibody|ATQ1 antibody|Betaine aldehyde dehydrogenase antibody|Delta1 piperideine 6 carboxylate dehydrogenease antibody|Delta1-piperideine-6-carboxylate dehydrogenase antibody|EPD antibody|P6c dehydrogenase antibody|PDE antibody|Anti-ALDH7A1 antibody [EP1934Y] (ab68192)

SCBT cat No: sc-514167|sc-365642|sc-376906|

Name

Rabbit polyclonal ALDH7A1 antibody

Catalogue No.

A8629

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ALDH7A1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:1000 – 1:4000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 58kDa/Observed: Refer to figures

Formulation

ALDH7A1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ALDH7A1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

EPD antibody, PDE antibody, ATQ1 antibody

Database links

Human UniProt/Swiss-Prot:P49419

Protein names

EPD, PDE, ATQ1

Protein function

Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism.

Protein tissue specificity

Abundant in hepatoma cells and fetal cochlea, ovary, eye, heart, adrenal gland, liver and kidney. Low levels present in adult peripheral blood leukocytes and fetal brain, thymus, spleen, skeletal muscle, lung and tongue.

Protein sequence and domain

Belongs to the aldehyde dehydrogenase family.

Protein cellular localization

Cytoplasm, cytosol . Nucleus .; Isoform 1: Mitochondrion .

Background

The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.

Note

AntibodyPlus can customize ALDH7A1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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