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Rabbit polyclonal ALKBH8 antibody (A7142)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:100 – 1:200 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal ALKBH8 antibody.
Check alternative names for the antibodyExpand
4930562C03Rik antibody|8030431D03Rik antibody|9430088N01Rik antibody|ABH8 antibody|alkB alkylation repair homolog 8 (E. coli) antibody|alkB alkylation repair homolog 8 antibody|AlkB homologue 8 antibody|ALKB8_HUMAN antibody|ALKBH8 antibody|Alkylated DNA repair protein alkB homolog 8 antibody|FLJ38204 antibody|MGC10235 antibody|OTTHUMP00000211286 antibody|OTTHUMP00000211287 antibody|Probable alpha-ketoglutarate-dependent dioxygenase ABH8 antibody|RGD1304687 antibody|S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 antibody|tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 antibody|Anti-ALKBH8 antibody (ab113512)
SCBT cat No: sc-101882|
Rabbit polyclonal ALKBH8 antibody
|Catalogue No.|| |
Recombinant protein of human ALKBH8
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 75kDa/Observed: Refer to figures
ALKBH8 antibody was tube-contained.
ALKBH8 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain . Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA . Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly) . Required for normal survival after DNA damage . May inhibit apoptosis and promote cell survival and angiogenesis .
|Protein tissue specificity|| |
Widely expressed, with highest expression in spleen, followed by pancreas and lung.
|Protein sequence and domain|| |
Belongs to the alkB family.; Contains 1 Fe2OG dioxygenase domain.; Contains 1 RRM (RNA recognition motif) domain.
|Protein cellular localization|| |
Cytoplasm . Nucleus . Note: Predominantly cytoplasmic.
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|Product type|| |
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