Rabbit polyclonal ALKBH8 antibody (A7142)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ALKBH8 antibody (A7142)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:100 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ABH8 antibody
4930562C03Rik antibody|8030431D03Rik antibody|9430088N01Rik antibody|ABH8 antibody|alkB alkylation repair homolog 8 (E. coli) antibody|alkB alkylation repair homolog 8 antibody|AlkB homologue 8 antibody|ALKB8_HUMAN antibody|ALKBH8 antibody|Alkylated DNA repair protein alkB homolog 8 antibody|FLJ38204 antibody|MGC10235 antibody|OTTHUMP00000211286 antibody|OTTHUMP00000211287 antibody|Probable alpha-ketoglutarate-dependent dioxygenase ABH8 antibody|RGD1304687 antibody|S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 antibody|tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 antibody|Anti-ALKBH8 antibody (ab113512)

SCBT cat No: sc-101882|

Name

Rabbit polyclonal ALKBH8 antibody

Catalogue No.

A7142

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human ALKBH8

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:100 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 75kDa/Observed: Refer to figures

Formulation

ALKBH8 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ALKBH8 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ABH8 antibody

Database links

Human UniProt/Swiss-Prot:Q96BT7

Protein names

ABH8

Protein function

Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain . Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA . Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly) . Required for normal survival after DNA damage . May inhibit apoptosis and promote cell survival and angiogenesis .

Protein tissue specificity

Widely expressed, with highest expression in spleen, followed by pancreas and lung.

Protein sequence and domain

Belongs to the alkB family.; Contains 1 Fe2OG dioxygenase domain.; Contains 1 RRM (RNA recognition motif) domain.

Protein cellular localization

Cytoplasm . Nucleus . Note: Predominantly cytoplasmic.

Note

AntibodyPlus can customize ALKBH8 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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