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Rabbit polyclonal ALOX15B antibody (A6865)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal ALOX15B antibody.
Check alternative names for the antibodyExpand
15 LO 2 antibody|15 LOX 2 antibody|15-lipoxygenase 2 antibody|15-LOX-2 antibody|15-LOX-B antibody|Alox15b antibody|Arachidonate 15 lipoxygenase second type antibody|Arachidonate 15 lipoxygenase type II antibody|Arachidonate 15-lipoxygenase B antibody|Arachidonate 15-lipoxygenase type II antibody|LX15B_HUMAN antibody|Anti-15 Lipoxygenase 2 antibody (ab23691)
SCBT cat No: sc-46048|sc-376871|sc-271290|sc-46049|sc-376795|sc-67142|sc-166387|sc-67143|
Rabbit polyclonal ALOX15B antibody
|Catalogue No.|| |
Recombinant protein of human ALOX15B
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 76kDa/Observed: Refer to figures
ALOX15B antibody was tube-contained.
ALOX15B antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.
|Protein tissue specificity|| |
Expressed in hair, prostate, lung, ovary, lymph node, spinal cord and cornea.
|Protein sequence and domain|| |
The PLAT domain can bind calcium ions; this promotes association with membranes.Belongs to the lipoxygenase family.; Contains 1 lipoxygenase domain.; Contains 1 PLAT domain.
|Protein cellular localization|| |
Isoform A: Nucleus. Note: Other isoforms are excluded from the nucleus.; Cytoplasm, cytosol. Cell membrane. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note: Predominantly cytosolic; becomes enriched at membranes upon calcium binding.
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
AntibodyPlus can customize ALOX15B antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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