Rabbit polyclonal ALS2 antibody (A7125)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ALS2 antibody (A7125)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ALSJ antibody, PLSJ antibody, IAHSP antibody, ALS2CR6 antibody
ALS 2 antibody|ALS2 antibody|ALS2_HUMAN antibody|ALS2CR6 antibody|Alsin antibody|ALSJ antibody|Amyotrophic lateral sclerosis 2 (juvenile) antibody|Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 6 antibody|Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein antibody|Amyotrophic lateral sclerosis 2 protein antibody|Amyotrophic lateral sclerosis protein 2 antibody|FLJ31851 antibody|IAHSP antibody|KIAA1563 antibody|MGC87187 antibody|PLSJ antibody|Anti-Als2 antibody [EPR11185] (ab170896)

SCBT cat No: sc-134256|sc-47947|

Name

Rabbit polyclonal ALS2 antibody

Catalogue No.

A7125

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human ALS2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 184kDa/Observed: Refer to figures

Formulation

ALS2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ALS2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ALSJ antibody, PLSJ antibody, IAHSP antibody, ALS2CR6 antibody

Database links

Human UniProt/Swiss-Prot:Q96Q42

Protein names

ALSJ, PLSJ, IAHSP, ALS2CR6

Protein function

May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity).

Protein sequence and domain

Contains 1 DH (DBL-homology) domain.; Contains 8 MORN repeats.; Contains 1 PH domain.; Contains 5 RCC1 repeats.; Contains 1 VPS9 domain.

Background

The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize ALS2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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