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Rabbit polyclonal ANAPC10 antibody (A8330)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal ANAPC10 antibody.
Check alternative names for the antibodyExpand
DOC1 antibody, APC10 antibody
ANAPC 10 antibody|anapc10 antibody|Anaphase promoting complex 10 antibody|Anaphase promoting complex subunit 10 antibody|Anaphase-promoting complex subunit 10 antibody|Apc 10 antibody|APC10 antibody|APC10_HUMAN antibody|Cyclosome subunit 10 antibody|DKFZP564L0562 antibody|Doc 1 antibody|Doc1 antibody|Doc1, S. cerevisiae, homolog of antibody|OTTHUMP00000220297 antibody|OTTHUMP00000220298 antibody|OTTHUMP00000220299 antibody|OTTHUMP00000220300 antibody|OTTHUMP00000220303 antibody|Anti-Apc10 antibody (ab106497)
SCBT cat No: sc-166790|sc-20989|
Rabbit polyclonal ANAPC10 antibody
|Catalogue No.|| |
Recombinant protein of human ANAPC10
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 21kDa/Observed: Refer to figures
ANAPC10 antibody was tube-contained.
ANAPC10 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
DOC1 antibody, APC10 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of ‘Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ‘Lys-48’- and ‘Lys-63’-linked polyubiquitin chains.
|Protein sequence and domain|| |
Belongs to the APC10 family.; Contains 1 DOC domain.
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001
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|Product type|| |
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