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Rabbit polyclonal ANAPC5 antibody (A7109)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal ANAPC5 antibody.
Check alternative names for the antibodyExpand
2510006G12Rik antibody|AA408751 antibody|AA536819 antibody|AA986414 antibody|ANAPC 5 antibody|ANAPC5 antibody|Anaphase promoting complex subunit 5 antibody|Anaphase-promoting complex subunit 5 antibody|Apc 5 antibody|APC5 antibody|APC5_HUMAN antibody|Cyclosome subunit 5 antibody|PDL 108 antibody|PDL108 antibody|Periodontal ligament fibroblast protein antibody|RMC1 antibody|Anti-Apc5 antibody (ab106487)
SCBT cat No: sc-25294|sc-20986|
Rabbit polyclonal ANAPC5 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human ANAPC5
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 85kDa/Observed: Refer to figures
ANAPC5 antibody was tube-contained.
ANAPC5 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of ‘Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ‘Lys-48’- and ‘Lys-63’-linked polyubiquitin chains.
|Protein sequence and domain|| |
The TPR repeats are six to seven residues longer than a canonical TPR motif.Belongs to the APC5 family.; Contains 13 TPR repeats.
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
AntibodyPlus can customize ANAPC5 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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