Rabbit polyclonal ANAPC5 antibody (A7109)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ANAPC5 antibody (A7109)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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APC5 antibody
2510006G12Rik antibody|AA408751 antibody|AA536819 antibody|AA986414 antibody|ANAPC 5 antibody|ANAPC5 antibody|Anaphase promoting complex subunit 5 antibody|Anaphase-promoting complex subunit 5 antibody|Apc 5 antibody|APC5 antibody|APC5_HUMAN antibody|Cyclosome subunit 5 antibody|PDL 108 antibody|PDL108 antibody|Periodontal ligament fibroblast protein antibody|RMC1 antibody|Anti-Apc5 antibody (ab106487)

SCBT cat No: sc-25294|sc-20986|

Name

Rabbit polyclonal ANAPC5 antibody

Catalogue No.

A7109

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ANAPC5

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 85kDa/Observed: Refer to figures

Formulation

ANAPC5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ANAPC5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

APC5 antibody

Database links

Human UniProt/Swiss-Prot:Q9UJX4

Protein names

APC5

Protein function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of ‘Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ‘Lys-48’- and ‘Lys-63’-linked polyubiquitin chains.

Protein sequence and domain

The TPR repeats are six to seven residues longer than a canonical TPR motif.Belongs to the APC5 family.; Contains 13 TPR repeats.

Background

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Research area

All research areas>Cell Cycle Proteins>Anaphase Promoting Complex
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize ANAPC5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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