Rabbit Polyclonal Anti-ATG14L antibody (STJ98935)


Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-ATG14L antibody (STJ98935)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


|4832427M01 antibody|BAKOR_HUMAN antibody|D14Ertd114e antibody|D14Ertd436e antibody|KIAA0831 antibody|mCG_6911 antibody|Anti-ATG14L antibody (ab139727)
SCBT cat No: sc-164767|


Anti-ATG14L antibody

Catalogue No.



Human, Mouse, Rat


Anti-ATG14L antibody detects endogenous ATG14L protein.


Recombinant Protein of ATG14L.





Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000







Molecular weight



Anti-ATG14L antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


Anti-ATG14L antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

4832427M01 antibody, BAKOR_HUMAN antibody, D14Ertd114e antibody, D14Ertd436e antibody, KIAA0831 antibody, mCG_6911 antibody

Database links


Protein function

Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity). .

Protein sequence and domain

Belongs to the ATG14 family. The coiled-coil domain is required for BECN1- and PIK3C3-binding and for autophagy. ; The final 80 residues in the C-terminus define a minimum required region for autophagosome binding called BATS. ; The N-terminal cysteine repeats are required for proper localization to the endoplasmic reticulum.

Protein cellular localization

Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Preautophagosomal structure membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Note=Cytosolic under nutrient-rich conditions (PubMed:19050071). Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071). Accumulates on highly curved PtdIns(3)P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity). .

Research area

All research areas>Synthesis and Degradation>Atg
(View all antibody categories related to Synthesis and Degradation)


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St John’s Laboratory Ltd.

Product type

Primary antibody


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