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Rabbit Polyclonal Anti-ATG4a antibody (STJ98928)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-ATG4a antibody.
Check alternative names for the antibodyExpand
|AI627006 antibody|AV169859 antibody|Cysteine protease ATG4A antibody|hAPG4A antibody|MGC107179 antibody|Anti-ATG4A antibody [EPR4122] (ab108322)
SCBT cat No: sc-131432|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-ATG4a antibody detects endogenous ATG4a protein.
Recombinant Protein of ATG4a.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-ATG4a antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-ATG4a antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
AI627006 antibody, AV169859 antibody, Cysteine protease ATG4A antibody, hAPG4A antibody, MGC107179 antibody
|Database links|| |
|Protein function|| |
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms. .
|Protein tissue specificity|| |
Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver. .
|Protein sequence and domain|| |
Belongs to the peptidase C54 family.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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