Rabbit Polyclonal Anti-ATG4c antibody (STJ98930)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-ATG4c antibody (STJ98930)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|APG4 autophagy 4 homolog C (S. cerevisiae) antibody|Cysteine protease ATG4C antibody|EC 3.4.22 antibody|FLJ14867 antibody|OTTHUMP00000010715 antibody|Anti-ATG4C antibody – C-terminal (ab191705)
SCBT cat No: sc-163708|

Name

Anti-ATG4c antibody

Catalogue No.

STJ98930

Reactivity

Human, Mouse, Rat

Specificity

Anti-ATG4c antibody detects endogenous ATG4c protein.

Immunogen

Recombinant Protein of ATG4c.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

57kDa

Formulation

Anti-ATG4c antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-ATG4c antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

APG4 autophagy 4 homolog C (S. cerevisiae) antibody, Cysteine protease ATG4C antibody, EC 3.4.22 antibody, FLJ14867 antibody, OTTHUMP00000010715 antibody

Database links

UniProt/Swiss-Prot:Q96DT6

Protein function

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. .

Protein tissue specificity

Highly expressed in skeletal muscle, heart, liver and testis. .

Protein sequence and domain

Belongs to the peptidase C54 family.

Protein cellular localization

Cytoplasm .

Research area

All research areas>Synthesis and Degradation>Atg
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize Anti-ATG4c antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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