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Rabbit Polyclonal Anti-ATG4c antibody (STJ98930)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-ATG4c antibody.
Check alternative names for the antibodyExpand
|APG4 autophagy 4 homolog C (S. cerevisiae) antibody|Cysteine protease ATG4C antibody|EC 3.4.22 antibody|FLJ14867 antibody|OTTHUMP00000010715 antibody|Anti-ATG4C antibody – C-terminal (ab191705)
SCBT cat No: sc-163708|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-ATG4c antibody detects endogenous ATG4c protein.
Recombinant Protein of ATG4c.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-ATG4c antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-ATG4c antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
APG4 autophagy 4 homolog C (S. cerevisiae) antibody, Cysteine protease ATG4C antibody, EC 3.4.22 antibody, FLJ14867 antibody, OTTHUMP00000010715 antibody
|Database links|| |
|Protein function|| |
Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. .
|Protein tissue specificity|| |
Highly expressed in skeletal muscle, heart, liver and testis. .
|Protein sequence and domain|| |
Belongs to the peptidase C54 family.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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