Rabbit Polyclonal Anti-BMPR-IB antibody (STJ98998)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-BMPR-IB antibody (STJ98998)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|Activin receptor like kinase 6 antibody|Acvrlk6 antibody|ALK 6 antibody|ALK6 antibody|alk6tr antibody|BMP type-1B receptor antibody|BMPR IB antibody|BMPR-1B antibody|Bmpr1b antibody|BMPRIB antibody|BMR1B_HUMAN antibody|Bone morphogenetic protein receptor type 1B antibody|Bone morphogenetic protein receptor type IB antibody|Bone morphogenetic protein receptor type-1B antibody|BR 1b antibody|BR1b antibody|CDw 293 antibody|CDw293 antibody|CDw293 antigen antibody|CFK 43a antibody|CFK43a antibody|Serine/threonine receptor kinase antibody|zALK 6 antibody|zALK6 antibody|Anti-BMPR1B antibody [MM0055-3E12] (ab78417)
SCBT cat No: sc-5678|sc-25454|sc-293175|sc-134285|

Name

Anti-BMPR-IB antibody

Catalogue No.

STJ98998

Reactivity

Human, Mouse

Specificity

Anti-BMPR-IB antibody detects endogenous BMPR-IB .

Immunogen

Synthetic peptide from human protein at AA range: 21-70.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-BMPR-IB antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-BMPR-IB antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Activin receptor like kinase 6 antibody, Acvrlk6 antibody, ALK 6 antibody, ALK6 antibody, alk6tr antibody, BMP type-1B receptor antibody, BMPR IB antibody, BMPR-1B antibody, Bmpr1b antibody, BMPRIB antibody, BMR1B_HUMAN antibody, Bone morphogenetic protein receptor type 1B antibody, Bone morphogenetic protein receptor type IB antibody, Bone morphogenetic protein receptor type-1B antibody, BR 1b antibody, BR1b antibody, CDw 293 antibody, CDw293 antibody, CDw293 antigen antibody, CFK 43a antibody, CFK43a antibody, Serine/threonine receptor kinase antibody, zALK 6 antibody, zALK6 antibody

Database links

UniProt/Swiss-Prot:O00238

Protein function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction. .

Involvement in disease

Acromesomelic dysplasia, Demirhan type (AMDD) [MIM:609441]: A form of chondrodysplasia. Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). . Note=The disease is caused by mutations affecting the gene represented in this entry.; Brachydactyly A2 (BDA2) [MIM:112600]: A form of brachydactyly. Brachydactyly defines a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. In brachydactyly type A2 shortening of the middle phalanges is confined to the index finger and the second toe, all other digits being more or less normal. Because of a rhomboid or triangular shape of the affected middle phalanx, the end of the second finger usually deviates radially. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Brachydactyly A1, D (BDA1D) [MIM:616849]: A form of brachydactyly type A1. Brachydactyly defines a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. Brachydactyly type A1 is characterized by middle phalanges of all the digits rudimentary or fused with the terminal phalanges. The proximal phalanges of the thumbs and big toes are short. BDA1D inheritance is autosomal dominant. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. ; Contains 1 GS domain. ; Contains 1 protein kinase domain.

Protein cellular localization

Cell membrane . Membrane; Single-pass type I membrane protein.

Research area

All research areas>Membrane Receptors>BMP Receptor
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize Anti-BMPR-IB antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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