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Rabbit Polyclonal Anti-Bob 1 antibody (STJ98803)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Bob 1 antibody.
Check alternative names for the antibodyExpand
|B cell Oct binding protein 1 antibody|B cell specific coactivator OBF 1 antibody|B cell specific coactivator OBF1 antibody|B-cell-specific coactivator OBF-1 antibody|BOB 1 antibody|BOB-1 antibody|OBF 1 antibody|OBF1 antibody|OBF1_HUMAN antibody|OCA B antibody|OCA-B antibody|OCAB antibody|OCT binding factor 1 antibody|OCT-binding factor 1 antibody|POU class 2 associating factor 1 antibody|POU domain class 2 associating factor 1 antibody|POU domain class 2-associating factor 1 antibody|Pou2af1 antibody|Anti-BOB1 antibody [EPR17685-34] (ab203825)
SCBT cat No: sc-130918|sc-23932|sc-955|sc-365595|sc-25402|sc-56817|
Anti-Bob 1 antibody
|Catalogue No.|| |
Anti-Bob 1 antibody detects endogenous Bob 1.
Synthetic peptide from human protein at AA range: 201-250.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-Bob 1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-Bob 1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
B cell Oct binding protein 1 antibody, B cell specific coactivator OBF 1 antibody, B cell specific coactivator OBF1 antibody, B-cell-specific coactivator OBF-1 antibody, BOB 1 antibody, BOB-1 antibody, OBF 1 antibody, OBF1 antibody, OBF1_HUMAN antibody, OCA B antibody, OCA-B antibody, OCAB antibody, OCT binding factor 1 antibody, OCT-binding factor 1 antibody, POU class 2 associating factor 1 antibody, POU domain class 2 associating factor 1 antibody, POU domain class 2-associating factor 1 antibody, Pou2af1 antibody
|Database links|| |
|Protein function|| |
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
|Protein tissue specificity|| |
|Involvement in disease|| |
Note=A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6. .
|Protein sequence and domain|| |
Belongs to the POU2AF1 family.
|Protein post-translational modifications|| |
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. .
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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