Rabbit Polyclonal Anti-Bob 1 antibody (STJ98803)

$99.00$319.00

Reactivity: Human
Applications: IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-Bob 1 antibody (STJ98803)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC-P, ELISA

Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|B cell Oct binding protein 1 antibody|B cell specific coactivator OBF 1 antibody|B cell specific coactivator OBF1 antibody|B-cell-specific coactivator OBF-1 antibody|BOB 1 antibody|BOB-1 antibody|OBF 1 antibody|OBF1 antibody|OBF1_HUMAN antibody|OCA B antibody|OCA-B antibody|OCAB antibody|OCT binding factor 1 antibody|OCT-binding factor 1 antibody|POU class 2 associating factor 1 antibody|POU domain class 2 associating factor 1 antibody|POU domain class 2-associating factor 1 antibody|Pou2af1 antibody|Anti-BOB1 antibody [EPR17685-34] (ab203825)
SCBT cat No: sc-130918|sc-23932|sc-955|sc-365595|sc-25402|sc-56817|

Name

Anti-Bob 1 antibody

Catalogue No.

STJ98803

Reactivity

Human

Specificity

Anti-Bob 1 antibody detects endogenous Bob 1.

Immunogen

Synthetic peptide from human protein at AA range: 201-250.

Host

Rabbit

Applications

IHC-P, ELISA

Recommended dilution

IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-Bob 1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-Bob 1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

B cell Oct binding protein 1 antibody, B cell specific coactivator OBF 1 antibody, B cell specific coactivator OBF1 antibody, B-cell-specific coactivator OBF-1 antibody, BOB 1 antibody, BOB-1 antibody, OBF 1 antibody, OBF1 antibody, OBF1_HUMAN antibody, OCA B antibody, OCA-B antibody, OCAB antibody, OCT binding factor 1 antibody, OCT-binding factor 1 antibody, POU class 2 associating factor 1 antibody, POU domain class 2 associating factor 1 antibody, POU domain class 2-associating factor 1 antibody, Pou2af1 antibody

Database links

UniProt/Swiss-Prot:Q16633

Protein function

Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.

Protein tissue specificity

B-cell specific.

Involvement in disease

Note=A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6. .

Protein sequence and domain

Belongs to the POU2AF1 family.

Protein post-translational modifications

Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. .

Protein cellular localization

Nucleus.

Note

AntibodyPlus can customize Anti-Bob 1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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