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Rabbit Polyclonal Anti-CD108 antibody (STJ98740)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-CD108 antibody.
Check alternative names for the antibodyExpand
SCBT cat No:
|Catalogue No.|| |
Human, Mouse, Rat
Anti-CD108 antibody detects endogenous CD108.
Synthetic peptide from human protein at AA range: 101-150.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-CD108 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-CD108 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Database links|| |
|Protein function|| |
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. .
|Protein tissue specificity|| |
Detected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level). Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney. .
|Protein sequence and domain|| |
Belongs to the semaphorin family. ; Contains 1 Ig-like C2-type (immunoglobulin-like) domain. ; Contains 1 PSI domain. ; Contains 1 Sema domain.
|Protein cellular localization|| |
Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side . Note=Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.
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St John’s Laboratory Ltd.
|Product type|| |
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