Rabbit Polyclonal Anti-CD11b antibody (STJ98736)

$99.00$319.00

Reactivity: Human
Applications: IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-CD11b antibody (STJ98736)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC-P, ELISA

Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|antigen CD11b (p170) antibody|Antigen CD11b p170 antibody|CD11 antigen like family member B antibody|CD11 antigen-like family member B antibody|CD11b antibody|CD11b/CD18 antibody|CD49d antibody|Cell surface glycoprotein MAC-1 subunit alpha antibody|Complement component 3 receptor 3 subunit antibody|Complement Component Receptor 3 Alpha antibody|Complement receptor type 3, alpha subunit antibody|CR 3 alpha chain (CR3A) antibody|CR 3 alpha chain antibody|CR-3 alpha chain antibody|CR3 antibody|CR3A antibody|F730045J24Rik antibody|Integrin Alpha M antibody|Integrin alpha M chain antibody|Integrin alpha-M antibody|Integrin beta 2 alpha subunit antibody|Integrin subunit alpha M antibody|integrin, alpha M (complement component 3 receptor 3 subunit) antibody|ITAM_HUMAN antibody|ITGAM antibody|Leukocyte adhesion receptor MO1 antibody|Ly-40 antibody|MAC 1 antibody|Mac-1a antibody|MAC1 antibody|Mac1, alpha subunit antibody|MAC1A antibody|Macrophage antigen alpha polypeptide antibody|MGC117044 antibody|Mo1, alpha subunit antibody|MO1A antibody|Neutrophil adherence receptor alpha M subunit antibody|Neutrophil adherence receptor antibody|SLEB6 antibody|Anti-CD11b/c antibody [OX42] (ab1211)
SCBT cat No:

Name

Anti-CD11b antibody

Catalogue No.

STJ98736

Reactivity

Human

Specificity

Anti-CD11b antibody detects endogenous CD11b.

Immunogen

Synthetic peptide from human protein at AA range: 280-360.

Host

Rabbit

Applications

IHC-P, ELISA

Recommended dilution

IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-CD11b antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-CD11b antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

antigen CD11b (p170) antibody, Antigen CD11b p170 antibody, CD11 antigen like family member B antibody, CD11 antigen-like family member B antibody, CD11b antibody, CD11b/CD18 antibody, CD49d antibody, Cell surface glycoprotein MAC-1 subunit alpha antibody, Complement component 3 receptor 3 subunit antibody, Complement Component Receptor 3 Alpha antibody, Complement receptor type 3, alpha subunit antibody, CR 3 alpha chain (CR3A) antibody, CR 3 alpha chain antibody, CR-3 alpha chain antibody, CR3 antibody, CR3A antibody, F730045J24Rik antibody, Integrin Alpha M antibody, Integrin alpha M chain antibody, Integrin alpha-M antibody, Integrin beta 2 alpha subunit antibody, Integrin subunit alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, ITAM_HUMAN antibody, ITGAM antibody, Leukocyte adhesion receptor MO1 antibody, Ly-40 antibody, MAC 1 antibody, Mac-1a antibody, MAC1 antibody, Mac1, alpha subunit antibody, MAC1A antibody, Macrophage antigen alpha polypeptide antibody, MGC117044 antibody, Mo1, alpha subunit antibody, MO1A antibody, Neutrophil adherence receptor alpha M subunit antibody, Neutrophil adherence receptor antibody, SLEB6 antibody

Database links

UniProt/Swiss-Prot:P11215

Protein function

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Protein tissue specificity

Predominantly expressed in monocytes and granulocytes.

Involvement in disease

Systemic lupus erythematosus 6 (SLEB6) [MIM:609939]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. . Note=Disease susceptibility may be associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the integrin alpha chain family. ; Contains 7 FG-GAP repeats. ; Contains 1 VWFA domain. The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Note

AntibodyPlus can customize Anti-CD11b antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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