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Rabbit Polyclonal Anti-CD204 antibody (STJ98763)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-CD204 antibody.
Check alternative names for the antibodyExpand
|CD204 antibody|CD204 antigen antibody|CD24 antibody|Macrophage acetylated LDL receptor I and II antibody|Macrophage scavenger receptor 1 antibody|Macrophage scavenger receptor type III antibody|Macrophage scavenger receptor types I and II antibody|Msr 1 antibody|MSR1 antibody|MSRE_HUMAN antibody|phSR1 antibody|phSR2 antibody|SCARA 1 antibody|SCARA1 antibody|Scavenger receptor class A member 1 antibody|Scavenger receptor type A antibody|Scvr antibody|SR A antibody|SRA antibody|Anti-Macrophage Scavenger Receptor I antibody (ab123946)
SCBT cat No:
|Catalogue No.|| |
Human, Mouse, Rat
Anti-CD204 antibody detects endogenous CD204.
Synthetic peptide from human protein at AA range: 241-290.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-CD204 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-CD204 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
CD204 antibody, CD204 antigen antibody, CD24 antibody, Macrophage acetylated LDL receptor I and II antibody, Macrophage scavenger receptor 1 antibody, Macrophage scavenger receptor type III antibody, Macrophage scavenger receptor types I and II antibody, Msr 1 antibody, MSR1 antibody, MSRE_HUMAN antibody, phSR1 antibody, phSR2 antibody, SCARA 1 antibody, SCARA1 antibody, Scavenger receptor class A member 1 antibody, Scavenger receptor type A antibody, Scvr antibody, SR A antibody, SRA antibody
|Database links|| |
|Protein function|| |
Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL) (PubMed:2251254). Isoform III does not internalize acetylated LDL (PubMed:9548586). .
|Protein tissue specificity|| |
Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain. .
|Involvement in disease|| |
Prostate cancer (PC) [MIM:176807]: A malignancy originating in tissues of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. . Note=The disease may be caused by mutations affecting the gene represented in this entry. MSR1 variants may play a role in susceptibility to prostate cancer. MSR1 variants have been found in individuals with prostate cancer and co-segregate with the disease in some families.; Barrett esophagus (BE) [MIM:614266]: A condition characterized by a metaplastic change in which normal esophageal squamous epithelium is replaced by a columnar and intestinal-type epithelium. Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes. . Note=The disease may be caused by mutations affecting the gene represented in this entry. Genetic variants in MSR1 have been found in individuals with Barrett esophagus and are thought to contribute to disease susceptibility.
|Protein sequence and domain|| |
Contains 1 collagen-like domain. ; Contains 1 SRCR domain.
|Protein cellular localization|| |
Membrane; Single-pass type II membrane protein.
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St John’s Laboratory Ltd.
|Product type|| |
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