Rabbit Polyclonal Anti-CD204 antibody (STJ98763)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-CD204 antibody (STJ98763)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC-P, ELISA

Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|CD204 antibody|CD204 antigen antibody|CD24 antibody|Macrophage acetylated LDL receptor I and II antibody|Macrophage scavenger receptor 1 antibody|Macrophage scavenger receptor type III antibody|Macrophage scavenger receptor types I and II antibody|Msr 1 antibody|MSR1 antibody|MSRE_HUMAN antibody|phSR1 antibody|phSR2 antibody|SCARA 1 antibody|SCARA1 antibody|Scavenger receptor class A member 1 antibody|Scavenger receptor type A antibody|Scvr antibody|SR A antibody|SRA antibody|Anti-Macrophage Scavenger Receptor I antibody (ab123946)
SCBT cat No:

Name

Anti-CD204 antibody

Catalogue No.

STJ98763

Reactivity

Human, Mouse, Rat

Specificity

Anti-CD204 antibody detects endogenous CD204.

Immunogen

Synthetic peptide from human protein at AA range: 241-290.

Host

Rabbit

Applications

IHC-P, ELISA

Recommended dilution

IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-CD204 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-CD204 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

CD204 antibody, CD204 antigen antibody, CD24 antibody, Macrophage acetylated LDL receptor I and II antibody, Macrophage scavenger receptor 1 antibody, Macrophage scavenger receptor type III antibody, Macrophage scavenger receptor types I and II antibody, Msr 1 antibody, MSR1 antibody, MSRE_HUMAN antibody, phSR1 antibody, phSR2 antibody, SCARA 1 antibody, SCARA1 antibody, Scavenger receptor class A member 1 antibody, Scavenger receptor type A antibody, Scvr antibody, SR A antibody, SRA antibody

Database links

UniProt/Swiss-Prot:P21757

Protein function

Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL) (PubMed:2251254). Isoform III does not internalize acetylated LDL (PubMed:9548586). .

Protein tissue specificity

Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain. .

Involvement in disease

Prostate cancer (PC) [MIM:176807]: A malignancy originating in tissues of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. . Note=The disease may be caused by mutations affecting the gene represented in this entry. MSR1 variants may play a role in susceptibility to prostate cancer. MSR1 variants have been found in individuals with prostate cancer and co-segregate with the disease in some families.; Barrett esophagus (BE) [MIM:614266]: A condition characterized by a metaplastic change in which normal esophageal squamous epithelium is replaced by a columnar and intestinal-type epithelium. Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes. . Note=The disease may be caused by mutations affecting the gene represented in this entry. Genetic variants in MSR1 have been found in individuals with Barrett esophagus and are thought to contribute to disease susceptibility.

Protein sequence and domain

Contains 1 collagen-like domain. ; Contains 1 SRCR domain.

Protein cellular localization

Membrane; Single-pass type II membrane protein.

Note

AntibodyPlus can customize Anti-CD204 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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