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Rabbit Polyclonal Anti-CD275 antibody (STJ99001)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
SCBT cat No:
|Catalogue No.|| |
Anti-CD275 antibody detects endogenous CD275 .
Synthetic peptide from human protein at AA range: 201-250.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
Anti-CD275 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-CD275 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Database links|| |
|Protein function|| |
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity). .
|Protein tissue specificity|| |
Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells. .
|Protein sequence and domain|| |
Belongs to the immunoglobulin superfamily. BTN/MOG family. ; Contains 1 Ig-like C2-type (immunoglobulin-like) domain. ; Contains 1 Ig-like V-type (immunoglobulin-like) domain.
|Protein cellular localization|| |
Membrane ; Single-pass type I membrane protein .
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St John’s Laboratory Ltd.
|Product type|| |
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