Rabbit Polyclonal Anti-CD299 antibody (STJ98766)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-CD299 antibody (STJ98766)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC-P, ELISA

Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|C type lectin domain family 4, member M antibody|DC SIGN2 antibody|DC-SIGN2 antibody|DCSIGNR antibody|Dendritic cell-specific ICAM-3-grabbing non-integrin 2 antibody|HP10347 antibody|L SIGN antibody|L-SIGN antibody|Liver/lymph node specific ICAM3 grabbing nonintegrin antibody|Liver/lymph node-specific ICAM-3-grabbing non-integrin antibody|LSIGN antibody|Mannose binding C type lectin DC SIGNR antibody|MGC129964 antibody|MGC47866 antibody|Anti-CD299 antibody (ab58603)
SCBT cat No: sc-53965|sc-53966|sc-74589|sc-20081|sc-271086|sc-17261|sc-390788|

Name

Anti-CD299 antibody

Catalogue No.

STJ98766

Reactivity

Human, Mouse, Rat

Specificity

Anti-CD299 antibody detects endogenous CD299.

Immunogen

Synthetic peptide from human protein at AA range: 271-320.

Host

Rabbit

Applications

WB, IHC-P, ELISA

Recommended dilution

WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

60kDa

Formulation

Anti-CD299 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-CD299 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

C type lectin domain family 4, member M antibody, DC SIGN2 antibody, DC-SIGN2 antibody, DCSIGNR antibody, Dendritic cell-specific ICAM-3-grabbing non-integrin 2 antibody, HP10347 antibody, L SIGN antibody, L-SIGN antibody, Liver/lymph node specific ICAM3 grabbing nonintegrin antibody, Liver/lymph node-specific ICAM-3-grabbing non-integrin antibody, LSIGN antibody, Mannose binding C type lectin DC SIGNR antibody, MGC129964 antibody, MGC47866 antibody

Database links

UniProt/Swiss-Prot:Q9H2X3

Protein function

Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. .; (Microbial infection) Acts as an attachment receptor for ebola virus (PubMed:12050398, PubMed:12502850). Acts as an attachment receptor for hepatitis C virus (PubMed:15371595, PubMed:16816373). Acts as an attachment receptor for HIV-1 (PubMed:21277928, PubMed:12502850). Acts as an attachment receptor for human coronavirus 229E (PubMed:17037540). Acts as an attachment receptor for human cytomegalovirus/HHV-5 (PubMed:12433371). Acts as an attachment receptor for influenzavirus (PubMed:21191006). Acts as an attachment receptor for SARS coronavirus (PubMed:15479853). Acts as an attachment receptor for west-nile virus (PubMed:16415006). Acts as an attachment receptor for Japanese encephalitis virus (PubMed:24623090). Acts as an attachment receptor for Marburg virus glycoprotein (PubMed:15479853). Recognition of M.bovis by dendritic cells may occur partially via this molecule (PubMed:21203928). .

Protein tissue specificity

Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells. .

Protein sequence and domain

Contains 1 C-type lectin domain. The tandem repeat domain, also called neck domain, mediates oligomerization.

Protein cellular localization

Isoform 1: Cell membrane ; Single-pass type II membrane protein .; Isoform 2: Cell membrane ; Single-pass type II membrane protein .; Isoform 3: Cell membrane ; Single-pass type II membrane protein .; Isoform 5: Secreted .; Isoform 6: Secreted .; Isoform 7: Secreted .; Isoform 10: Secreted .

Research area

All research areas>Lymphocyte Signaling>CD209
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize Anti-CD299 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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