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Rabbit Polyclonal Anti-CD299 antibody (STJ98766)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC-P, ELISA
Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-CD299 antibody.
Check alternative names for the antibodyExpand
|C type lectin domain family 4, member M antibody|DC SIGN2 antibody|DC-SIGN2 antibody|DCSIGNR antibody|Dendritic cell-specific ICAM-3-grabbing non-integrin 2 antibody|HP10347 antibody|L SIGN antibody|L-SIGN antibody|Liver/lymph node specific ICAM3 grabbing nonintegrin antibody|Liver/lymph node-specific ICAM-3-grabbing non-integrin antibody|LSIGN antibody|Mannose binding C type lectin DC SIGNR antibody|MGC129964 antibody|MGC47866 antibody|Anti-CD299 antibody (ab58603)
SCBT cat No: sc-53965|sc-53966|sc-74589|sc-20081|sc-271086|sc-17261|sc-390788|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-CD299 antibody detects endogenous CD299.
Synthetic peptide from human protein at AA range: 271-320.
WB, IHC-P, ELISA
|Recommended dilution|| |
WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
|Molecular weight|| |
Anti-CD299 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-CD299 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
C type lectin domain family 4, member M antibody, DC SIGN2 antibody, DC-SIGN2 antibody, DCSIGNR antibody, Dendritic cell-specific ICAM-3-grabbing non-integrin 2 antibody, HP10347 antibody, L SIGN antibody, L-SIGN antibody, Liver/lymph node specific ICAM3 grabbing nonintegrin antibody, Liver/lymph node-specific ICAM-3-grabbing non-integrin antibody, LSIGN antibody, Mannose binding C type lectin DC SIGNR antibody, MGC129964 antibody, MGC47866 antibody
|Database links|| |
|Protein function|| |
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. .; (Microbial infection) Acts as an attachment receptor for ebola virus (PubMed:12050398, PubMed:12502850). Acts as an attachment receptor for hepatitis C virus (PubMed:15371595, PubMed:16816373). Acts as an attachment receptor for HIV-1 (PubMed:21277928, PubMed:12502850). Acts as an attachment receptor for human coronavirus 229E (PubMed:17037540). Acts as an attachment receptor for human cytomegalovirus/HHV-5 (PubMed:12433371). Acts as an attachment receptor for influenzavirus (PubMed:21191006). Acts as an attachment receptor for SARS coronavirus (PubMed:15479853). Acts as an attachment receptor for west-nile virus (PubMed:16415006). Acts as an attachment receptor for Japanese encephalitis virus (PubMed:24623090). Acts as an attachment receptor for Marburg virus glycoprotein (PubMed:15479853). Recognition of M.bovis by dendritic cells may occur partially via this molecule (PubMed:21203928). .
|Protein tissue specificity|| |
Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells. .
|Protein sequence and domain|| |
Contains 1 C-type lectin domain. The tandem repeat domain, also called neck domain, mediates oligomerization.
|Protein cellular localization|| |
Isoform 1: Cell membrane ; Single-pass type II membrane protein .; Isoform 2: Cell membrane ; Single-pass type II membrane protein .; Isoform 3: Cell membrane ; Single-pass type II membrane protein .; Isoform 5: Secreted .; Isoform 6: Secreted .; Isoform 7: Secreted .; Isoform 10: Secreted .
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St John’s Laboratory Ltd.
|Product type|| |
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