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Rabbit Polyclonal Anti-CD3 zeta antibody (STJ98995)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
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SCBT cat No:
Anti-CD3 zeta antibody
|Catalogue No.|| |
Anti-CD3 zeta antibody detects endogenous CD3 zeta .
Synthetic peptide from human protein at AA range: 51-100.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
Anti-CD3 zeta antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-CD3 zeta antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Database links|| |
|Protein function|| |
Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
|Involvement in disease|| |
Immunodeficiency 25 (IMD25) [MIM:610163]: An immunological deficiency characterized by T-cells impaired immune response to alloantigens, tetanus toxoid and mitogens. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the CD3Z/FCER1G family. ; Contains 3 ITAM domains. The ITAM domains mediate interaction with SHB.
|Protein post-translational modifications|| |
Phosphorylated on Tyr residues after T-cell receptor triggering. .
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
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St John’s Laboratory Ltd.
|Product type|| |
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