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Rabbit Polyclonal Anti-CD303 antibody (STJ98744)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
SCBT cat No:
|Catalogue No.|| |
Anti-CD303 antibody detects endogenous CD303.
Synthetic peptide from human protein at AA range: 91-140.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-CD303 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-CD303 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Database links|| |
|Protein function|| |
Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose. .
|Protein tissue specificity|| |
Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha. .
|Protein sequence and domain|| |
Contains 1 C-type lectin domain.
|Protein cellular localization|| |
Membrane ; Single-pass type II membrane protein .
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St John’s Laboratory Ltd.
|Product type|| |
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