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Rabbit Polyclonal Anti-COL13A1 antibody (STJ99344)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-COL13A1 antibody.
Check alternative names for the antibodyExpand
|CODA1_HUMAN antibody|COL13A1 antibody|collagen type XIII alpha 1 antibody|collagen alpha 1(XIII) chain antibody|Collagen alpha-1(XIII) chain antibody|COLXIIIA1 antibody|Anti-COL13A1 antibody (ab111397)
SCBT cat No: sc-167513|sc-167514|
|Catalogue No.|| |
Anti-COL13A1 antibody detects endogenous levels of COL13A1.
Synthesized peptide derived from human COL13A1. at AA range: 41-90.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-COL13A1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-COL13A1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
CODA1_HUMAN antibody, COL13A1 antibody, collagen type XIII alpha 1 antibody, collagen alpha 1(XIII) chain antibody, Collagen alpha-1(XIII) chain antibody, COLXIIIA1 antibody
|Database links|| |
|Protein function|| |
Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane. May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin. At neuromuscular junctions, may play a role in acetylcholine receptor clustering (PubMed:26626625). .
|Protein tissue specificity|| |
Widely expressed in both fetal and adult ocular tissues (at protein level). In the eye, expression is accentuated in the ciliary muscle, optic nerve and the neural retina. In early placenta, localized to fibroblastoid stromal cells of the placental villi, to endothelial cells of developing capillaries and to cells of the cytotrophoblastic columns. Also detected in large decidual cells of the decidual membrane and to stromal cells of the gestational endometrium, but not in the epithelial cells in the endometrial glands. Isoform 10: Expressed in muscle (PubMed:26626625). .
|Involvement in disease|| |
Myasthenic syndrome, congenital, 19 (CMS19) [MIM:616720]: A form of congenital myasthenic syndrome, a group of disorders characterized by failure of neuromuscular transmission, including pre-synaptic, synaptic, and post-synaptic disorders that are not of autoimmune origin. Clinical features are easy fatigability and muscle weakness affecting the axial and limb muscles (with hypotonia in early-onset forms), the ocular muscles (leading to ptosis and ophthalmoplegia), and the facial and bulbar musculature (affecting sucking and swallowing, and leading to dysphonia). The symptoms fluctuate and worsen with physical effort. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein cellular localization|| |
Cell membrane ; Single-pass type II membrane protein . Cell junction, synapse, postsynaptic cell membrane .
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St John’s Laboratory Ltd.
|Product type|| |
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