Rabbit Polyclonal Anti-COL13A1 antibody (STJ99344)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-COL13A1 antibody (STJ99344)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|CODA1_HUMAN antibody|COL13A1 antibody|collagen type XIII alpha 1 antibody|collagen alpha 1(XIII) chain antibody|Collagen alpha-1(XIII) chain antibody|COLXIIIA1 antibody|Anti-COL13A1 antibody (ab111397)
SCBT cat No: sc-167513|sc-167514|

Name

Anti-COL13A1 antibody

Catalogue No.

STJ99344

Reactivity

Human, Mouse

Specificity

Anti-COL13A1 antibody detects endogenous levels of COL13A1.

Immunogen

Synthesized peptide derived from human COL13A1. at AA range: 41-90.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

70kDa

Formulation

Anti-COL13A1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-COL13A1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

CODA1_HUMAN antibody, COL13A1 antibody, collagen type XIII alpha 1 antibody, collagen alpha 1(XIII) chain antibody, Collagen alpha-1(XIII) chain antibody, COLXIIIA1 antibody

Database links

UniProt/Swiss-Prot:Q5TAT6

Protein function

Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane. May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin. At neuromuscular junctions, may play a role in acetylcholine receptor clustering (PubMed:26626625). .

Protein tissue specificity

Widely expressed in both fetal and adult ocular tissues (at protein level). In the eye, expression is accentuated in the ciliary muscle, optic nerve and the neural retina. In early placenta, localized to fibroblastoid stromal cells of the placental villi, to endothelial cells of developing capillaries and to cells of the cytotrophoblastic columns. Also detected in large decidual cells of the decidual membrane and to stromal cells of the gestational endometrium, but not in the epithelial cells in the endometrial glands. Isoform 10: Expressed in muscle (PubMed:26626625). .

Involvement in disease

Myasthenic syndrome, congenital, 19 (CMS19) [MIM:616720]: A form of congenital myasthenic syndrome, a group of disorders characterized by failure of neuromuscular transmission, including pre-synaptic, synaptic, and post-synaptic disorders that are not of autoimmune origin. Clinical features are easy fatigability and muscle weakness affecting the axial and limb muscles (with hypotonia in early-onset forms), the ocular muscles (leading to ptosis and ophthalmoplegia), and the facial and bulbar musculature (affecting sucking and swallowing, and leading to dysphonia). The symptoms fluctuate and worsen with physical effort. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein cellular localization

Cell membrane ; Single-pass type II membrane protein . Cell junction, synapse, postsynaptic cell membrane .

Note

AntibodyPlus can customize Anti-COL13A1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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