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Rabbit Polyclonal Anti-Cystatin A antibody (STJ98707)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC-P, ELISA
Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Cystatin A antibody.
Check alternative names for the antibodyExpand
|AREI antibody|cstA antibody|Cystatin A antibody|Cystatin AS antibody|Cystatin-A antibody|Cystatin-AS antibody|CYTA_HUMAN antibody|Stefin A antibody|Stefin-A antibody|STF1 antibody|STFA antibody|Anti-Cystatin A antibody [WR-23/2/3/3] (ab10442)
SCBT cat No: sc-376759|sc-33277|sc-32803|
Anti-Cystatin A antibody
|Catalogue No.|| |
Anti-Cystatin A antibody detects endogenous Cystatin A.
Synthetic peptide from human protein at AA range: 60-98.
WB, IHC-P, ELISA
|Recommended dilution|| |
WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
|Molecular weight|| |
Anti-Cystatin A antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-Cystatin A antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
AREI antibody, cstA antibody, Cystatin A antibody, Cystatin AS antibody, Cystatin-A antibody, Cystatin-AS antibody, CYTA_HUMAN antibody, Stefin A antibody, Stefin-A antibody, STF1 antibody, STFA antibody
|Database links|| |
|Protein function|| |
This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. .
|Protein tissue specificity|| |
Expressed in the skin throughout the epidermis. .
|Involvement in disease|| |
Peeling skin syndrome 4 (PSS4) [MIM:607936]: A genodermatosis characterized by congenital exfoliative ichthyosis, sharing some features with ichthyosis bullosa of Siemens and annular epidermolytic ichthyosis. PSS4 presents shortly after birth as dry, scaly skin over most of the body with coarse peeling of non-erythematous skin on the palms and soles, which is exacerbated by excessive moisture and minor trauma. Electron microscopy analysis of skin biopsies, reveals mostly normal-appearing upper layers of the epidermis, but prominent intercellular edema of the basal and suprabasal cell layers with aggregates of tonofilaments in the basal keratinocytes. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the cystatin family.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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