No products in the cart.
Rabbit Polyclonal Anti-DAAM1 antibody (STJ98677)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-DAAM1 antibody.
Check alternative names for the antibodyExpand
SCBT cat No:
|Catalogue No.|| |
Anti-DAAM1 antibody detects endogenous DAAM1.
Synthetic peptide from human protein at AA range: 400-500.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:5000-20000
|Molecular weight|| |
Anti-DAAM1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-DAAM1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Database links|| |
|Protein function|| |
Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). .
|Protein tissue specificity|| |
Expressed in all tissues examined.
|Protein sequence and domain|| |
Belongs to the formin homology family. ; Contains 1 DAD (diaphanous autoregulatory) domain. ; Contains 1 FH1 (formin homology 1) domain. ; Contains 1 FH2 (formin homology 2) domain. ; Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. The C-terminal DAD domain may participate in intramolecular interactions with the N-terminus.; The DAD domain regulates activation via by an autoinhibitory interaction with the GBD/FH3 domain. This autoinhibition is released upon competitive binding of an activated GTPase. The release of DAD allows the FH2 domain to then nucleate and elongate nonbranched actin filaments (By similarity).
|Protein cellular localization|| |
Cytoplasm . Cytoplasm, cytoskeleton, cilium basal body . Note=Perinuclear.
AntibodyPlus can customize Anti-DAAM1 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: