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Rabbit Polyclonal Anti-Dsg1 antibody (STJ98723)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC-P, ELISA
Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Dsg1 antibody.
Check alternative names for the antibodyExpand
|Cadherin family member 4 antibody|CDHF4 antibody|Desmoglein-1 antibody|Desmosomal glycoprotein 1 antibody|DG1 antibody|DGI antibody|DSG antibody|DSG1 antibody|DSG1_HUMAN antibody|EPKHE antibody|EPKHIA antibody|Pemphigus foliaceus antigen antibody|PPKS1 antibody|SPPK1 antibody|Anti-Desmoglein 1 antibody [27B2] (ab12077)
SCBT cat No: sc-23910|sc-59904|sc-137164|sc-14857|sc-20114|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-Dsg1 antibody detects endogenous Dsg1.
Synthetic peptide from human protein at AA range: 30-90.
WB, IHC-P, ELISA
|Recommended dilution|| |
WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
|Molecular weight|| |
Anti-Dsg1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-Dsg1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Cadherin family member 4 antibody, CDHF4 antibody, Desmoglein-1 antibody, Desmosomal glycoprotein 1 antibody, DG1 antibody, DGI antibody, DSG antibody, DSG1 antibody, DSG1_HUMAN antibody, EPKHE antibody, EPKHIA antibody, Pemphigus foliaceus antigen antibody, PPKS1 antibody, SPPK1 antibody
|Database links|| |
|Protein function|| |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
|Protein tissue specificity|| |
Epidermis, tongue, tonsil and esophagus.
|Involvement in disease|| |
Palmoplantar keratoderma 1, striate, focal, or diffuse (PPKS1) [MIM:148700]: A dermatological disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper IgE (EPKHE) [MIM:615508]: A syndrome characterized by severe dermatitis, multiple allergies and metabolic wasting. Clinical features include erythroderma, yellowish papules and plaques arranged at the periphery of the palms, along the fingers and over weight-bearing areas of the feet, skin erosions and scaling, and hypotrichosis. Additionally, patients manifest severe food allergies, elevated immunoglobulin E (IgE) levels and recurrent infections with marked metabolic wasting. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Contains 4 cadherin domains. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
|Protein cellular localization|| |
Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome.
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St John’s Laboratory Ltd.
|Product type|| |
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