Rabbit Polyclonal Anti-Dsg1 antibody (STJ98723)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-Dsg1 antibody (STJ98723)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC-P, ELISA

Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-Dsg1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

|Cadherin family member 4 antibody|CDHF4 antibody|Desmoglein-1 antibody|Desmosomal glycoprotein 1 antibody|DG1 antibody|DGI antibody|DSG antibody|DSG1 antibody|DSG1_HUMAN antibody|EPKHE antibody|EPKHIA antibody|Pemphigus foliaceus antigen antibody|PPKS1 antibody|SPPK1 antibody|Anti-Desmoglein 1 antibody [27B2] (ab12077)
SCBT cat No: sc-23910|sc-59904|sc-137164|sc-14857|sc-20114|

Name

Anti-Dsg1 antibody

Catalogue No.

STJ98723

Reactivity

Human, Mouse, Rat

Specificity

Anti-Dsg1 antibody detects endogenous Dsg1.

Immunogen

Synthetic peptide from human protein at AA range: 30-90.

Host

Rabbit

Applications

WB, IHC-P, ELISA

Recommended dilution

WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

160kDa

Formulation

Anti-Dsg1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-Dsg1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Cadherin family member 4 antibody, CDHF4 antibody, Desmoglein-1 antibody, Desmosomal glycoprotein 1 antibody, DG1 antibody, DGI antibody, DSG antibody, DSG1 antibody, DSG1_HUMAN antibody, EPKHE antibody, EPKHIA antibody, Pemphigus foliaceus antigen antibody, PPKS1 antibody, SPPK1 antibody

Database links

UniProt/Swiss-Prot:Q02413

Protein function

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Protein tissue specificity

Epidermis, tongue, tonsil and esophagus.

Involvement in disease

Palmoplantar keratoderma 1, striate, focal, or diffuse (PPKS1) [MIM:148700]: A dermatological disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper IgE (EPKHE) [MIM:615508]: A syndrome characterized by severe dermatitis, multiple allergies and metabolic wasting. Clinical features include erythroderma, yellowish papules and plaques arranged at the periphery of the palms, along the fingers and over weight-bearing areas of the feet, skin erosions and scaling, and hypotrichosis. Additionally, patients manifest severe food allergies, elevated immunoglobulin E (IgE) levels and recurrent infections with marked metabolic wasting. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 4 cadherin domains. Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome.

Note

AntibodyPlus can customize Anti-Dsg1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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