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Rabbit Polyclonal Anti-EGF antibody (STJ98714)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC-P, ELISA
Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-EGF antibody.
Check alternative names for the antibodyExpand
|Beta urogastrone antibody|EGF antibody|EGF_HUMAN antibody|Epidermal growth factor antibody|HOMG4 antibody|OTTHUMP00000219721 antibody|OTTHUMP00000219722 antibody|Pro epidermal growth factor antibody|URG antibody|Urogastrone antibody|Anti-EGF antibody (ab9695)
SCBT cat No: sc-1342|
|Catalogue No.|| |
Anti-EGF antibody detects endogenous EGF.
Synthetic peptide from human protein at AA range: 1000-1060.
WB, IHC-P, ELISA
|Recommended dilution|| |
WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
|Molecular weight|| |
Anti-EGF antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-EGF antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Beta urogastrone antibody, EGF antibody, EGF_HUMAN antibody, Epidermal growth factor antibody, HOMG4 antibody, OTTHUMP00000219721 antibody, OTTHUMP00000219722 antibody, Pro epidermal growth factor antibody, URG antibody, Urogastrone antibody
|Database links|| |
|Protein function|| |
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941). .
|Protein tissue specificity|| |
Expressed in kidney, salivary gland, cerebrum and prostate. .
|Involvement in disease|| |
Hypomagnesemia 4 (HOMG4) [MIM:611718]: A disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to moderate psychomotor retardation, and brisk tendon reflexes. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Contains 9 EGF-like domains. ; Contains 9 LDL-receptor class B repeats.
|Protein post-translational modifications|| |
O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor). .
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
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St John’s Laboratory Ltd.
|Product type|| |
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