Rabbit Polyclonal Anti-Endoglin antibody (STJ98713)

$99.00$319.00

Reactivity: Human
Applications: WB, IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-Endoglin antibody (STJ98713)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC-P, ELISA

Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-Endoglin antibody.

Alternative names:

Check alternative names for the antibody

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|AI528660 antibody|AI662476 antibody|CD 105 antibody|CD105 antibody|CD105 antigen antibody|EGLN_HUMAN antibody|END antibody|Endoglin antibody|Eng antibody|FLJ41744 antibody|HHT1 antibody|ORW antibody|ORW1 antibody|Osler Rendu Weber syndrome 1 antibody|RP11 228B15.2 antibody|S-endoglin antibody|SN6 antibody|Anti-CD105 antibody [SN6] (ab11414)
SCBT cat No: sc-71042|sc-21787|sc-53999|sc-376381|sc-19790|sc-20632|sc-19793|sc-18893|sc-18838|sc-20072|sc-101443|

Name

Anti-Endoglin antibody

Catalogue No.

STJ98713

Reactivity

Human

Specificity

Anti-Endoglin antibody detects endogenous Endoglin.

Immunogen

Synthetic peptide from human protein at AA range: 370-430.

Host

Rabbit

Applications

WB, IHC-P, ELISA

Recommended dilution

WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

70kDa

Formulation

Anti-Endoglin antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-Endoglin antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

AI528660 antibody, AI662476 antibody, CD 105 antibody, CD105 antibody, CD105 antigen antibody, EGLN_HUMAN antibody, END antibody, Endoglin antibody, Eng antibody, FLJ41744 antibody, HHT1 antibody, ORW antibody, ORW1 antibody, Osler Rendu Weber syndrome 1 antibody, RP11 228B15.2 antibody, S-endoglin antibody, SN6 antibody

Database links

UniProt/Swiss-Prot:P17813

Protein function

Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3. .

Protein tissue specificity

Endoglin is restricted to endothelial cells in all tissues except bone marrow.

Involvement in disease

Telangiectasia, hereditary hemorrhagic, 1 (HHT1) [MIM:187300]: A multisystemic vascular dysplasia leading to dilation of permanent blood vessels and arteriovenous malformations of skin, mucosa, and viscera. The disease is characterized by recurrent epistaxis and gastro-intestinal hemorrhage. Visceral involvement includes arteriovenous malformations of the lung, liver, and brain. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Research area

All research areas>Membrane Receptors>Endoglin
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize Anti-Endoglin antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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