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Rabbit Polyclonal Anti-Endoglin antibody (STJ98713)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC-P, ELISA
Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Endoglin antibody.
Check alternative names for the antibodyExpand
|AI528660 antibody|AI662476 antibody|CD 105 antibody|CD105 antibody|CD105 antigen antibody|EGLN_HUMAN antibody|END antibody|Endoglin antibody|Eng antibody|FLJ41744 antibody|HHT1 antibody|ORW antibody|ORW1 antibody|Osler Rendu Weber syndrome 1 antibody|RP11 228B15.2 antibody|S-endoglin antibody|SN6 antibody|Anti-CD105 antibody [SN6] (ab11414)
SCBT cat No: sc-71042|sc-21787|sc-53999|sc-376381|sc-19790|sc-20632|sc-19793|sc-18893|sc-18838|sc-20072|sc-101443|
|Catalogue No.|| |
Anti-Endoglin antibody detects endogenous Endoglin.
Synthetic peptide from human protein at AA range: 370-430.
WB, IHC-P, ELISA
|Recommended dilution|| |
WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
|Molecular weight|| |
Anti-Endoglin antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-Endoglin antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
AI528660 antibody, AI662476 antibody, CD 105 antibody, CD105 antibody, CD105 antigen antibody, EGLN_HUMAN antibody, END antibody, Endoglin antibody, Eng antibody, FLJ41744 antibody, HHT1 antibody, ORW antibody, ORW1 antibody, Osler Rendu Weber syndrome 1 antibody, RP11 228B15.2 antibody, S-endoglin antibody, SN6 antibody
|Database links|| |
|Protein function|| |
Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3. .
|Protein tissue specificity|| |
Endoglin is restricted to endothelial cells in all tissues except bone marrow.
|Involvement in disease|| |
Telangiectasia, hereditary hemorrhagic, 1 (HHT1) [MIM:187300]: A multisystemic vascular dysplasia leading to dilation of permanent blood vessels and arteriovenous malformations of skin, mucosa, and viscera. The disease is characterized by recurrent epistaxis and gastro-intestinal hemorrhage. Visceral involvement includes arteriovenous malformations of the lung, liver, and brain. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
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St John’s Laboratory Ltd.
|Product type|| |
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