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Rabbit Polyclonal Anti-FA2H antibody (STJ99320)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-FA2H antibody.
Check alternative names for the antibodyExpand
|FA2H antibody|FA2H_HUMAN antibody|FAAH antibody|FAH1 antibody|Fatty acid 2 hydroxylase antibody|Fatty acid 2-hydroxylase antibody|Fatty acid alpha hydroxylase antibody|Fatty acid alpha-hydroxylase antibody|Fatty acid hydroxylase domain containing 1 antibody|FAXDC1 antibody|FLJ25287 antibody|SCS7 antibody|Spastic paraplegia 35 (autosomal recessive) antibody|SPG35 antibody|Anti-FA2H antibody (ab175093)
SCBT cat No: sc-161044|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-FA2H antibody detects endogenous levels of FA2H.
Synthesized peptide derived from human FA2H. at AA range: 101-150.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-FA2H antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-FA2H antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
FA2H antibody, FA2H_HUMAN antibody, FAAH antibody, FAH1 antibody, Fatty acid 2 hydroxylase antibody, Fatty acid 2-hydroxylase antibody, Fatty acid alpha hydroxylase antibody, Fatty acid alpha-hydroxylase antibody, Fatty acid hydroxylase domain containing 1 antibody, FAXDC1 antibody, FLJ25287 antibody, SCS7 antibody, Spastic paraplegia 35 (autosomal recessive) antibody, SPG35 antibody
|Database links|| |
|Protein function|| |
Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids. .
|Protein tissue specificity|| |
Detected in differentiating cultured keratinocytes (at protein level). Detected in epidermis and cultured keratinocytes. Highly expressed in brain and colon. Detected at lower levels in testis, prostate, pancreas and kidney. .
|Involvement in disease|| |
Spastic paraplegia 35, autosomal recessive (SPG35) [MIM:612319]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. SPG35 is a complicated form characterized by childhood onset of gait difficulties. It has a rapid progression and many patients become wheelchair-bound as young adults. Patients manifest cognitive decline associated with leukodystrophy. Other variable neurologic features, such as dystonia, optic atrophy, and seizures may also occur. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the sterol desaturase family. SCS7 subfamily. ; Contains 1 cytochrome b5 heme-binding domain. The histidine box domains may contain the active site and/or be involved in metal ion binding.
|Protein cellular localization|| |
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein .
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St John’s Laboratory Ltd.
|Product type|| |
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