Rabbit Polyclonal Anti-FA2H antibody (STJ99320)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-FA2H antibody (STJ99320)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|FA2H antibody|FA2H_HUMAN antibody|FAAH antibody|FAH1 antibody|Fatty acid 2 hydroxylase antibody|Fatty acid 2-hydroxylase antibody|Fatty acid alpha hydroxylase antibody|Fatty acid alpha-hydroxylase antibody|Fatty acid hydroxylase domain containing 1 antibody|FAXDC1 antibody|FLJ25287 antibody|SCS7 antibody|Spastic paraplegia 35 (autosomal recessive) antibody|SPG35 antibody|Anti-FA2H antibody (ab175093)
SCBT cat No: sc-161044|

Name

Anti-FA2H antibody

Catalogue No.

STJ99320

Reactivity

Human, Mouse, Rat

Specificity

Anti-FA2H antibody detects endogenous levels of FA2H.

Immunogen

Synthesized peptide derived from human FA2H. at AA range: 101-150.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

55kDa

Formulation

Anti-FA2H antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-FA2H antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

FA2H antibody, FA2H_HUMAN antibody, FAAH antibody, FAH1 antibody, Fatty acid 2 hydroxylase antibody, Fatty acid 2-hydroxylase antibody, Fatty acid alpha hydroxylase antibody, Fatty acid alpha-hydroxylase antibody, Fatty acid hydroxylase domain containing 1 antibody, FAXDC1 antibody, FLJ25287 antibody, SCS7 antibody, Spastic paraplegia 35 (autosomal recessive) antibody, SPG35 antibody

Database links

UniProt/Swiss-Prot:Q7L5A8

Protein function

Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids. .

Protein tissue specificity

Detected in differentiating cultured keratinocytes (at protein level). Detected in epidermis and cultured keratinocytes. Highly expressed in brain and colon. Detected at lower levels in testis, prostate, pancreas and kidney. .

Involvement in disease

Spastic paraplegia 35, autosomal recessive (SPG35) [MIM:612319]: A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. SPG35 is a complicated form characterized by childhood onset of gait difficulties. It has a rapid progression and many patients become wheelchair-bound as young adults. Patients manifest cognitive decline associated with leukodystrophy. Other variable neurologic features, such as dystonia, optic atrophy, and seizures may also occur. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the sterol desaturase family. SCS7 subfamily. ; Contains 1 cytochrome b5 heme-binding domain. The histidine box domains may contain the active site and/or be involved in metal ion binding.

Protein cellular localization

Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein .

Note

AntibodyPlus can customize Anti-FA2H antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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