No products in the cart.
Rabbit Polyclonal Anti-GADD34 antibody (STJ98676)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-GADD34 antibody.
Check alternative names for the antibodyExpand
|Apoptosis associated protein antibody|GADD 34 antibody|Growth arrest and DNA damage inducible 34 antibody|Growth arrest and DNA damage-inducible protein GADD34 antibody|Myeloid differentiation primary response protein MyD116 homolog antibody|Ppp1r15a antibody|PR15A_HUMAN antibody|Protein phosphatase 1 regulatory (inhibitor) subunit 15A antibody|Protein phosphatase 1 regulatory subunit 15A antibody|Anti-GADD34 antibody (ab9869)
SCBT cat No: sc-825|
|Catalogue No.|| |
Anti-GADD34 antibody detects endogenous GADD34.
Synthetic peptide from human protein at AA range: 430-490.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:5000-20000
|Molecular weight|| |
Anti-GADD34 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-GADD34 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Apoptosis associated protein antibody, GADD 34 antibody, Growth arrest and DNA damage inducible 34 antibody, Growth arrest and DNA damage-inducible protein GADD34 antibody, Myeloid differentiation primary response protein MyD116 homolog antibody, Ppp1r15a antibody, PR15A_HUMAN antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 15A antibody, Protein phosphatase 1 regulatory subunit 15A antibody
|Database links|| |
|Protein function|| |
Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'. .
|Protein sequence and domain|| |
Belongs to the PPP1R15 family.
|Protein post-translational modifications|| |
Phosphorylated at multiple Ser/Thr residues. Phosphorylated on tyrosine by LYN; which impairs its antiproliferative activity. Phosphorylation at Tyr-262 enhances proteasomal degradation, this position is dephosphorylated by PTPN2. .; Polyubiquitinated. Exhibits a rapid proteasomal degradation with a half-life under 1 hour, ubiquitination depends on endoplasmic reticulum association. .
|Protein cellular localization|| |
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side . Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side . Note=Associates with membranes via an N-terminal amphipathic intramembrane region. .
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Tumor-SuppressorApoptosis/">Tumor Suppressor/Apoptosis</a>><a href="http://antibodyplus.com/product-tag/GADD/">GADD</a><br><a href="http://antibodyplus.com/product-tag/Tumor-SuppressorApoptosis/"> (View all antibody categories related to Tumor Suppressor/Apoptosis)</a>
AntibodyPlus can customize Anti-GADD34 antibody according to your requirement, including bulk product size,etc. Please contact <a href="mailto:email@example.com">firstname.lastname@example.org</a>. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: