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Rabbit Polyclonal Anti-Gl Syn antibody (STJ98853)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:5000-20023
Recommended protocols: check protocols
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SCBT cat No:
Anti-Gl Syn antibody
|Catalogue No.|| |
Human, Mouse, Rat
Anti-Gl Syn antibody detects endogenous levels of Gl Syn.
Synthesized peptide derived from Human Gl Syn at AA range: 301-350.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:5000-20023
Anti-Gl Syn antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Gl Syn antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Database links|| |
|Protein function|| |
This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts. .
|Involvement in disease|| |
Congenital systemic glutamine deficiency (CSGD) [MIM:610015]: Rare developmental disorder with severe brain malformation resulting in multi-organ failure and neonatal death. Glutamine is largely absent from affected patients serum, urine and cerebrospinal fluid. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the glutamine synthetase family.
|Protein post-translational modifications|| |
Ubiquitinated by ZNRF1. .
|Protein cellular localization|| |
Cytoplasm. Mitochondrion .
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St John’s Laboratory Ltd.
|Product type|| |
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