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Rabbit Polyclonal Anti-GRIN1 antibody (STJ98859)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:5000-20029
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-GRIN1 antibody.
Check alternative names for the antibodyExpand
|GluN1 antibody|Glutamate [NMDA] receptor subunit zeta-1 antibody|Glutamate receptor ionotropic N methyl D aspartate 1 antibody|Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1 antibody|glutamate receptor ionotropic, NMDA 1 antibody|Grin1 antibody|MRD8 antibody|N methyl D aspartate receptor antibody|N methyl D aspartate receptor channel subunit zeta 1 antibody|N methyl D aspartate receptor subunit NR1 antibody|N-methyl-D-aspartate receptor subunit NR1 antibody|NMD-R1 antibody|NMDA 1 antibody|NMDA R1 antibody|NMDA receptor 1 antibody|NMDA1 antibody|NMDAR antibody|NMDZ1_HUMAN antibody|NR1 antibody|Anti-NMDAR1 antibody – Neuronal Marker (ab17345)
SCBT cat No: sc-1467|sc-9058|sc-138479|sc-138481|sc-9484|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-GRIN1 antibody detects endogenous levels of GRIN1.
Synthesized peptide derived from Human GRIN1 at AA range: 840-880.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:5000-20029
Anti-GRIN1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-GRIN1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
GluN1 antibody, Glutamate [NMDA] receptor subunit zeta-1 antibody, Glutamate receptor ionotropic N methyl D aspartate 1 antibody, Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1 antibody, glutamate receptor ionotropic, NMDA 1 antibody, Grin1 antibody, MRD8 antibody, N methyl D aspartate receptor antibody, N methyl D aspartate receptor channel subunit zeta 1 antibody, N methyl D aspartate receptor subunit NR1 antibody, N-methyl-D-aspartate receptor subunit NR1 antibody, NMD-R1 antibody, NMDA 1 antibody, NMDA R1 antibody, NMDA receptor 1 antibody, NMDA1 antibody, NMDAR antibody, NMDZ1_HUMAN antibody, NR1 antibody
|Database links|| |
|Protein function|| |
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity). .
|Involvement in disease|| |
Mental retardation, autosomal dominant 8 (MRD8) [MIM:614254]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
|Protein post-translational modifications|| |
NMDA is probably regulated by C-terminal phosphorylation of an isoform of NR1 by PKC. Dephosphorylated on Ser-897 probably by protein phosphatase 2A (PPP2CB). Its phosphorylated state is influenced by the formation of the NMDAR-PPP2CB complex and the NMDAR channel activity. .
|Protein cellular localization|| |
Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. .
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St John’s Laboratory Ltd.
|Product type|| |
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