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Rabbit Polyclonal Anti-Histone H2A.Z antibody (STJ98947)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Histone H2A.Z antibody.
Check alternative names for the antibodyExpand
|H2A/z antibody|H2afz antibody|H2AZ antibody|H2AZ_HUMAN antibody|Histone H2A.Z antibody|Acetyl anti-H2A.Z (K4 + K7 + K11) antibody – ChIP Grade (ab18262)
SCBT cat No: sc-67218|
Anti-Histone H2A.Z antibody
|Catalogue No.|| |
Human, Mouse, Rat
Anti-Histone H2A.Z antibody detects endogenous Histone H2A.Z.
Synthetic peptide from human protein at AA range: 1-30.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Histone H2A.Z antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Histone H2A.Z antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
H2A/z antibody, H2afz antibody, H2AZ antibody, H2AZ_HUMAN antibody, Histone H2A.Z antibody
|Database links|| |
|Protein function|| |
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. .
|Protein sequence and domain|| |
Belongs to the histone H2A family.
|Protein post-translational modifications|| |
Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression. .; Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis (By similarity). .; Monomethylated on Lys-5 and Lys-8 by SETD6. SETD6 predominantly methylates Lys-8, lys-5 being a possible secondary site. .; Not phosphorylated. .
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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