Rabbit Polyclonal Anti-Histone H2A.Z antibody (STJ98947)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-Histone H2A.Z antibody (STJ98947)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|H2A/z antibody|H2afz antibody|H2AZ antibody|H2AZ_HUMAN antibody|Histone H2A.Z antibody|Acetyl anti-H2A.Z (K4 + K7 + K11) antibody – ChIP Grade (ab18262)
SCBT cat No: sc-67218|

Name

Anti-Histone H2A.Z antibody

Catalogue No.

STJ98947

Reactivity

Human, Mouse, Rat

Specificity

Anti-Histone H2A.Z antibody detects endogenous Histone H2A.Z.

Immunogen

Synthetic peptide from human protein at AA range: 1-30.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

20kDa

Formulation

Anti-Histone H2A.Z antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-Histone H2A.Z antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

H2A/z antibody, H2afz antibody, H2AZ antibody, H2AZ_HUMAN antibody, Histone H2A.Z antibody

Database links

UniProt/Swiss-Prot:P0C0S5

Protein function

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. .

Protein sequence and domain

Belongs to the histone H2A family.

Protein post-translational modifications

Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression. .; Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis (By similarity). .; Monomethylated on Lys-5 and Lys-8 by SETD6. SETD6 predominantly methylates Lys-8, lys-5 being a possible secondary site. .; Not phosphorylated. .

Protein cellular localization

Nucleus. Chromosome.

Research area

All research areas>Transcription Regulators>Histone
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize Anti-Histone H2A.Z antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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