Rabbit Polyclonal Anti-HLA-DMbeta antibody (STJ98988)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-HLA-DMbeta antibody (STJ98988)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|class II antigen HLA-DM beta chain antibody|class II histocompatibility antigen antibody|Class II histocompatibility antigen M beta chain antibody|D6S221E antibody|DMB antibody|HLA class II histocompatibility antigen DM beta chain antibody|HLA-DM histocompatibility type, beta chain antibody|M beta chain antibody|Major histocompatibility complex class II DM beta antibody|MHC class II antigen DMB antibody|MHC class II antigen HLA DM beta chain antibody|MHC class II HLA DMB antibody|OTTHUMP00000029257 antibody|Really interesting new gene 7 protein antibody|RING 7 antibody|RING7 antibody|Anti-HLA DMB antibody [EPR7982] (ab131273)
SCBT cat No: sc-69738|sc-393548|sc-14539|

Name

Anti-HLA-DMbeta antibody

Catalogue No.

STJ98988

Reactivity

Human

Specificity

Anti-HLA-DMbeta antibody detects endogenous HLA-DMbeta .

Immunogen

Synthetic peptide from human protein at AA range: 40-100.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-HLA-DMbeta antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-HLA-DMbeta antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

class II antigen HLA-DM beta chain antibody, class II histocompatibility antigen antibody, Class II histocompatibility antigen M beta chain antibody, D6S221E antibody, DMB antibody, HLA class II histocompatibility antigen DM beta chain antibody, HLA-DM histocompatibility type, beta chain antibody, M beta chain antibody, Major histocompatibility complex class II DM beta antibody, MHC class II antigen DMB antibody, MHC class II antigen HLA DM beta chain antibody, MHC class II HLA DMB antibody, OTTHUMP00000029257 antibody, Really interesting new gene 7 protein antibody, RING 7 antibody, RING7 antibody

Database links

UniProt/Swiss-Prot:P28068

Protein function

Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. .

Protein sequence and domain

Belongs to the MHC class II family. ; Contains 1 Ig-like C1-type (immunoglobulin-like) domain. The YXXZ (Tyr-Xaa-Xaa-Zaa, where Zaa is a hydrophobic residue) motif mediates the targeting to the lysosomal compartments.

Protein cellular localization

Late endosome membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Note=Localizes to late endocytic compartment. Associates with lysosome membranes.

Research area

All research areas>Lymphocyte Signaling>HLA
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize Anti-HLA-DMbeta antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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