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Rabbit Polyclonal Anti-HLA-DMbeta antibody (STJ98988)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-HLA-DMbeta antibody.
Check alternative names for the antibodyExpand
|class II antigen HLA-DM beta chain antibody|class II histocompatibility antigen antibody|Class II histocompatibility antigen M beta chain antibody|D6S221E antibody|DMB antibody|HLA class II histocompatibility antigen DM beta chain antibody|HLA-DM histocompatibility type, beta chain antibody|M beta chain antibody|Major histocompatibility complex class II DM beta antibody|MHC class II antigen DMB antibody|MHC class II antigen HLA DM beta chain antibody|MHC class II HLA DMB antibody|OTTHUMP00000029257 antibody|Really interesting new gene 7 protein antibody|RING 7 antibody|RING7 antibody|Anti-HLA DMB antibody [EPR7982] (ab131273)
SCBT cat No: sc-69738|sc-393548|sc-14539|
|Catalogue No.|| |
Anti-HLA-DMbeta antibody detects endogenous HLA-DMbeta .
Synthetic peptide from human protein at AA range: 40-100.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
Anti-HLA-DMbeta antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-HLA-DMbeta antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
class II antigen HLA-DM beta chain antibody, class II histocompatibility antigen antibody, Class II histocompatibility antigen M beta chain antibody, D6S221E antibody, DMB antibody, HLA class II histocompatibility antigen DM beta chain antibody, HLA-DM histocompatibility type, beta chain antibody, M beta chain antibody, Major histocompatibility complex class II DM beta antibody, MHC class II antigen DMB antibody, MHC class II antigen HLA DM beta chain antibody, MHC class II HLA DMB antibody, OTTHUMP00000029257 antibody, Really interesting new gene 7 protein antibody, RING 7 antibody, RING7 antibody
|Database links|| |
|Protein function|| |
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. .
|Protein sequence and domain|| |
Belongs to the MHC class II family. ; Contains 1 Ig-like C1-type (immunoglobulin-like) domain. The YXXZ (Tyr-Xaa-Xaa-Zaa, where Zaa is a hydrophobic residue) motif mediates the targeting to the lysosomal compartments.
|Protein cellular localization|| |
Late endosome membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Lymphocyte-Signaling/">Lymphocyte Signaling</a>><a href="http://antibodyplus.com/product-tag/HLA/">HLA</a><br><a href="http://antibodyplus.com/product-tag/Lymphocyte-Signaling/"> (View all antibody categories related to Lymphocyte Signaling)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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