Rabbit Polyclonal Anti-HNF-4alpha (Acetyl Lys106) antibody (STJ98691)


Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal Anti-HNF-4alpha (Acetyl Lys106) antibody (STJ98691)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-HNF-4alpha (Acetyl Lys106) antibody.

Alternative names:

Check alternative names for the antibody


SCBT cat No:


Anti-HNF-4alpha (Acetyl Lys106) antibody

Catalogue No.



Human, Mouse, Rat


Anti-HNF-4alpha (Acetyl Lys106) antibody detects endogenous HNF-4alpha when Acetyl occurs at Lys106.


Synthetic Acetyl peptide from human protein at AA range: 106.





Recommended dilution

WB 1:500-2000; ELISA 1:5000-20000







Molecular weight



Anti-HNF-4alpha (Acetyl Lys106) antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.


1 mg/ml


Anti-HNF-4alpha (Acetyl Lys106) antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Database links


Protein function

Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine.

Involvement in disease

Maturity-onset diabetes of the young 1 (MODY1) [MIM:125850]: A form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Diabetes mellitus, non-insulin-dependent (NIDDM) [MIM:125853]: A multifactorial disorder of glucose homeostasis caused by a lack of sensitivity to the body’s own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. . Note=Disease susceptibility may be associated with variations affecting the gene represented in this entry.; Fanconi renotubular syndrome 4 with maturity-onset diabetes of the young (FRTS4) [MIM:616026]: A disease characterized by Fanconi syndrome associated with a beta cell phenotype of neonatal hyperinsulinism with macrosomia and young onset diabetes. Fanconi syndrome is a proximal tubulopathy resulting in generalised aminoaciduria, low molecular weight proteinuria, glycosuria, hyperphosphaturia and hypouricemia. Some FRTS4 patients have nephrocalcinosis, renal impairment, hypercalciuria with relative hypocalcemia, and hypermagnesemia. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the nuclear hormone receptor family. NR2 subfamily. ; Contains 1 nuclear receptor DNA-binding domain.

Protein post-translational modifications

Phosphorylated on tyrosine residue(s); phosphorylation is important for its DNA-binding activity. Phosphorylation may directly or indirectly play a regulatory role in the subnuclear distribution. Phosphorylation at Ser-313 by AMPK reduces the ability to form homodimers and bind DNA. .; Acetylation at Lys-458 lowers transcriptional activation by about two-fold. .

Protein cellular localization



AntibodyPlus can customize Anti-HNF-4alpha (Acetyl Lys106) antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.


St John’s Laboratory Ltd.

Product type

Primary antibody


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:

Welcome to AntibodyPlus!