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Rabbit Polyclonal Anti-IgD antibody (STJ98800)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-IgD antibody.
Check alternative names for the antibodyExpand
|IGHD antibody|Constant region of heavy chain of IgD antibody|Ig delta chain C region antibody|Ig delta chain C region secreted form antibody|IgD antibody|Igh-5 antibody|Immunoglobulin delta antibody|Immunoglobulin heavy constant delta antibody|Immunoglobulin heavy delta chain antibody|Anti-IGHD antibody [EPR6146] (ab124795)
SCBT cat No: sc-53345|sc-53082|sc-393519|
|Catalogue No.|| |
Anti-IgD antibody detects endogenous IgD.
Synthetic peptide from human protein at AA range: 111-160.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-IgD antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-IgD antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
IGHD antibody, Constant region of heavy chain of IgD antibody, Ig delta chain C region antibody, Ig delta chain C region secreted form antibody, IgD antibody, Igh-5 antibody, Immunoglobulin delta antibody, Immunoglobulin heavy constant delta antibody, Immunoglobulin heavy delta chain antibody
|Database links|| |
|Protein function|| |
IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. .
|Protein sequence and domain|| |
Contains 3 Ig-like (immunoglobulin-like) domains.
|Protein cellular localization|| |
Isoform 1: Secreted.; Isoform 2: Cell membrane; Single-pass type I membrane protein.
AntibodyPlus can customize Anti-IgD antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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