Rabbit Polyclonal Anti-IgD antibody (STJ98800)

$99.00$319.00

Reactivity: Human
Applications: IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal Anti-IgD antibody (STJ98800)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC-P, ELISA

Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-IgD antibody.

Alternative names:

Check alternative names for the antibody

Expand

|IGHD antibody|Constant region of heavy chain of IgD antibody|Ig delta chain C region antibody|Ig delta chain C region secreted form antibody|IgD antibody|Igh-5 antibody|Immunoglobulin delta antibody|Immunoglobulin heavy constant delta antibody|Immunoglobulin heavy delta chain antibody|Anti-IGHD antibody [EPR6146] (ab124795)
SCBT cat No: sc-53345|sc-53082|sc-393519|

Name

Anti-IgD antibody

Catalogue No.

STJ98800

Reactivity

Human

Specificity

Anti-IgD antibody detects endogenous IgD.

Immunogen

Synthetic peptide from human protein at AA range: 111-160.

Host

Rabbit

Applications

IHC-P, ELISA

Recommended dilution

IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-IgD antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-IgD antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

IGHD antibody, Constant region of heavy chain of IgD antibody, Ig delta chain C region antibody, Ig delta chain C region secreted form antibody, IgD antibody, Igh-5 antibody, Immunoglobulin delta antibody, Immunoglobulin heavy constant delta antibody, Immunoglobulin heavy delta chain antibody

Database links

UniProt/Swiss-Prot:P01880

Protein function

IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. .

Protein sequence and domain

Contains 3 Ig-like (immunoglobulin-like) domains.

Protein cellular localization

Isoform 1: Secreted.; Isoform 2: Cell membrane; Single-pass type I membrane protein.

Research area

All research areas>Lymphocyte Signaling>Immunoglobulin
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize Anti-IgD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!