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Rabbit Polyclonal Anti-IL-1F6 antibody (STJ98792)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-IL-1F6 antibody.
Check alternative names for the antibodyExpand
|FIL1 antibody|FIL1 epsilon antibody|FIL1(EPSILON) antibody|FIL1E antibody|IL 1 epsilon antibody|IL 1F6 antibody|IL 1H1 antibody|IL-1 epsilon antibody|IL-1F6 antibody|IL1E antibody|IL1F6 antibody|IL1F6_HUMAN antibody|IL1RP2 antibody|IL36A antibody|Interleukin 1 epsilon antibody|Interleukin 1 family member 6 (epsilon) antibody|Interleukin 1 family member 6 antibody|Interleukin 36 alpha antibody|Interleukin-1 epsilon antibody|Interleukin-1 family member 6 antibody|MGC129552 antibody|MGC129553 antibody|MGC151479 antibody|MGC151481 antibody|OTTMUSP00000012798 antibody|RP23-176J12.4 antibody|Anti-IL37 antibody (ab57187)
SCBT cat No: sc-517072|sc-168152|sc-168153|
|Catalogue No.|| |
Anti-IL-1F6 antibody detects endogenous IL-1F6.
Synthetic peptide from human protein at AA range: 21-70.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-IL-1F6 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-IL-1F6 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
FIL1 antibody, FIL1 epsilon antibody, FIL1(EPSILON) antibody, FIL1E antibody, IL 1 epsilon antibody, IL 1F6 antibody, IL 1H1 antibody, IL-1 epsilon antibody, IL-1F6 antibody, IL1E antibody, IL1F6 antibody, IL1F6_HUMAN antibody, IL1RP2 antibody, IL36A antibody, Interleukin 1 epsilon antibody, Interleukin 1 family member 6 (epsilon) antibody, Interleukin 1 family member 6 antibody, Interleukin 36 alpha antibody, Interleukin-1 epsilon antibody, Interleukin-1 family member 6 antibody, MGC129552 antibody, MGC129553 antibody, MGC151479 antibody, MGC151481 antibody, OTTMUSP00000012798 antibody, RP23-176J12.4 antibody
|Database links|| |
|Protein function|| |
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation. In cultured keratinocytes induces the expression of macrophage, T-cell, and neutrophil chemokines, such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CL20, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20 and CXCL1, and the production of proinflammatory cytokines such as TNF-alpha, IL-8 and IL-6. In cultured monocytes upregulates expression of IL-1A, IL-1B and IL-6. In myeloid dendritic cells involved in cell maturation by upregulating surface expression of CD83, CD86 and HLA-DR. In monocyte-derived dendritic cells facilitates dendritic cell maturation and drives T-cell proliferation. May play a role in proinflammatory effects in the lung. .
|Protein tissue specificity|| |
Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin. .
|Protein sequence and domain|| |
Belongs to the IL-1 family.
|Protein post-translational modifications|| |
N-terminal truncation leads to a dramatic enhancement of its activity (>1000-fold). .
|Protein cellular localization|| |
AntibodyPlus can customize Anti-IL-1F6 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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