Rabbit Polyclonal Anti-IL-1F7 antibody (STJ98774)

$99.00$319.00

Reactivity: Human
Applications: IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-IL-1F7 antibody (STJ98774)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC-P, ELISA

Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|FIL1 antibody|Interleukin 1 superfamily z antibody|Interleukin-23 antibody|Anti-IL37 antibody (ab57187)
SCBT cat No: sc-517072|sc-168152|sc-168153|

Name

Anti-IL-1F7 antibody

Catalogue No.

STJ98774

Reactivity

Human

Specificity

Anti-IL-1F7 antibody detects endogenous IL-1F7.

Immunogen

Synthetic peptide from human protein at AA range: 101-150.

Host

Rabbit

Applications

IHC-P, ELISA

Recommended dilution

IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-IL-1F7 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-IL-1F7 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

FIL1 antibody, Interleukin 1 superfamily z antibody, Interleukin-23 antibody

Database links

UniProt/Swiss-Prot:Q9NZH6

Protein function

Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation. .

Protein tissue specificity

In general, low constitutive expression, if any, in healthy tissues; high expression in inflammatory counterparts, including in synovial tissues from individuals with active rheumatoid arthritis. Isoform A, isoform B and isoform C are expressed in testis, colon, placenta, lung and lymph node. Isoform D and isoform E were found only in testis and bone marrow. Whereas only isoform A is found in brain, only isoform B in kidney and only isoform C in heart. .

Protein sequence and domain

Belongs to the IL-1 family.

Protein post-translational modifications

Proteolytically converted to the mature form by CASP1.

Protein cellular localization

Cytoplasm, cytosol . Nucleus . Secreted . Note=Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions (PubMed:20935647). Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation (PubMed:18390730).

Research area

All research areas>Membrane Receptors>IL-1F
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize Anti-IL-1F7 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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