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Rabbit Polyclonal Anti-IL16 antibody (STJ98673)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-IL16 antibody.
Check alternative names for the antibodyExpand
|HGNC:5980 antibody|HsT19289 antibody|IL-16 antibody|IL16 antibody|IL16_HUMAN antibody|Interleukin 16 precursor antibody|Interleukin-16 antibody|LCF antibody|Lymphocyte chemoattractant factor antibody|Neuronal interleukin 16 antibody|NIL16 antibody|prIL 16 antibody|PrIL16 antibody|Prointerleukin 16 antibody|Anti-IL16 antibody [EPR19988] (ab207181)
SCBT cat No: sc-374606|sc-374604|sc-1941|sc-374605|sc-7902|
|Catalogue No.|| |
Anti-IL16 antibody detects endogenous IL16.
Synthetic peptide from human protein at AA range: 900-960.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:5000-20000
|Molecular weight|| |
Anti-IL16 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-IL16 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
HGNC:5980 antibody, HsT19289 antibody, IL-16 antibody, IL16 antibody, IL16_HUMAN antibody, Interleukin 16 precursor antibody, Interleukin-16 antibody, LCF antibody, Lymphocyte chemoattractant factor antibody, Neuronal interleukin 16 antibody, NIL16 antibody, prIL 16 antibody, PrIL16 antibody, Prointerleukin 16 antibody
|Database links|| |
|Protein function|| |
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.; Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.; Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
|Protein tissue specificity|| |
Isoform 3 is expressed in hemopoietic tissues, such as resting T-cells, but is undetectable during active T-cell proliferation.
|Protein sequence and domain|| |
Contains 4 PDZ (DHR) domains.
|Protein post-translational modifications|| |
Isoform 3 is synthesized as a chemo-attractant inactive precursor in hemopoietic tissues and is proteolytically cleaved by caspase-3 to yield IL-16. .
|Protein cellular localization|| |
Interleukin-16: Secreted.; Isoform 1: Cytoplasm .; Isoform 3: Cytoplasm. Nucleus.
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St John’s Laboratory Ltd.
|Product type|| |
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