Rabbit Polyclonal Anti-IL16 antibody (STJ98673)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-IL16 antibody (STJ98673)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|HGNC:5980 antibody|HsT19289 antibody|IL-16 antibody|IL16 antibody|IL16_HUMAN antibody|Interleukin 16 precursor antibody|Interleukin-16 antibody|LCF antibody|Lymphocyte chemoattractant factor antibody|Neuronal interleukin 16 antibody|NIL16 antibody|prIL 16 antibody|PrIL16 antibody|Prointerleukin 16 antibody|Anti-IL16 antibody [EPR19988] (ab207181)
SCBT cat No: sc-374606|sc-374604|sc-1941|sc-374605|sc-7902|

Name

Anti-IL16 antibody

Catalogue No.

STJ98673

Reactivity

Human

Specificity

Anti-IL16 antibody detects endogenous IL16.

Immunogen

Synthetic peptide from human protein at AA range: 900-960.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

67kDa

Formulation

Anti-IL16 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-IL16 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

HGNC:5980 antibody, HsT19289 antibody, IL-16 antibody, IL16 antibody, IL16_HUMAN antibody, Interleukin 16 precursor antibody, Interleukin-16 antibody, LCF antibody, Lymphocyte chemoattractant factor antibody, Neuronal interleukin 16 antibody, NIL16 antibody, prIL 16 antibody, PrIL16 antibody, Prointerleukin 16 antibody

Database links

UniProt/Swiss-Prot:Q14005

Protein function

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.; Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.; Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Protein tissue specificity

Isoform 3 is expressed in hemopoietic tissues, such as resting T-cells, but is undetectable during active T-cell proliferation.

Protein sequence and domain

Contains 4 PDZ (DHR) domains.

Protein post-translational modifications

Isoform 3 is synthesized as a chemo-attractant inactive precursor in hemopoietic tissues and is proteolytically cleaved by caspase-3 to yield IL-16. .

Protein cellular localization

Interleukin-16: Secreted.; Isoform 1: Cytoplasm .; Isoform 3: Cytoplasm. Nucleus.

Note

AntibodyPlus can customize Anti-IL16 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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