Rabbit Polyclonal Anti-Keratin-pan antibody (STJ98693)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-Keratin-pan antibody (STJ98693)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|CK 2e antibody|Cytokeratin-2e antibody|Epithelial keratin-2e antibody|K2e antibody|Keratin type II cytoskeletal 2 epidermal antibody|Keratin-2 epidermis antibody|KRT2 antibody|KRT2A antibody|KRT2E antibody|Type-II keratin Kb2 antibody|Anti-Cytokeratin 2e antibody [Ks2.342.7.1] (ab19122)
SCBT cat No: sc-58731|sc-49179|

Name

Anti-Keratin-pan antibody

Catalogue No.

STJ98693

Reactivity

Human, Mouse, Rat

Specificity

Anti-Keratin-pan antibody detects endogenous Keratin-pan.

Immunogen

Synthetic peptide from human protein at AA range: 150-220.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

70kDa

Formulation

Anti-Keratin-pan antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-Keratin-pan antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

CK 2e antibody, Cytokeratin-2e antibody, Epithelial keratin-2e antibody, K2e antibody, Keratin type II cytoskeletal 2 epidermal antibody, Keratin-2 epidermis antibody, KRT2 antibody, KRT2A antibody, KRT2E antibody, Type-II keratin Kb2 antibody

Database links

UniProt/Swiss-Prot:P35908

Protein function

Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. .

Protein tissue specificity

Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization. .

Involvement in disease

Ichthyosis bullosa of Siemens (IBS) [MIM:146800]: A rare autosomal dominant skin disorder displaying a type of epidermolytic hyperkeratosis characterized by generalized erythema and extensive blistering from birth. Large, dark gray hyperkeratoses are observed in later weeks. The skin of IBS patients is unusually fragile and has a tendency to shed the outer layers of the epidermis, producing localized denuded areas (molting effect). IBS usually improves with age so that in most middle-aged patients the hyperkeratosis and keratotic lichenification is limited to the flexural folds of the major joints. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the intermediate filament family.

Research area

All research areas>Structural Proteins>Cytokeratin
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize Anti-Keratin-pan antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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