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Rabbit Polyclonal Anti-Keratin-pan antibody (STJ98693)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Keratin-pan antibody.
Check alternative names for the antibodyExpand
|CK 2e antibody|Cytokeratin-2e antibody|Epithelial keratin-2e antibody|K2e antibody|Keratin type II cytoskeletal 2 epidermal antibody|Keratin-2 epidermis antibody|KRT2 antibody|KRT2A antibody|KRT2E antibody|Type-II keratin Kb2 antibody|Anti-Cytokeratin 2e antibody [Ks2.342.7.1] (ab19122)
SCBT cat No: sc-58731|sc-49179|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-Keratin-pan antibody detects endogenous Keratin-pan.
Synthetic peptide from human protein at AA range: 150-220.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:5000-20000
|Molecular weight|| |
Anti-Keratin-pan antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-Keratin-pan antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
CK 2e antibody, Cytokeratin-2e antibody, Epithelial keratin-2e antibody, K2e antibody, Keratin type II cytoskeletal 2 epidermal antibody, Keratin-2 epidermis antibody, KRT2 antibody, KRT2A antibody, KRT2E antibody, Type-II keratin Kb2 antibody
|Database links|| |
|Protein function|| |
Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. .
|Protein tissue specificity|| |
Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization. .
|Involvement in disease|| |
Ichthyosis bullosa of Siemens (IBS) [MIM:146800]: A rare autosomal dominant skin disorder displaying a type of epidermolytic hyperkeratosis characterized by generalized erythema and extensive blistering from birth. Large, dark gray hyperkeratoses are observed in later weeks. The skin of IBS patients is unusually fragile and has a tendency to shed the outer layers of the epidermis, producing localized denuded areas (molting effect). IBS usually improves with age so that in most middle-aged patients the hyperkeratosis and keratotic lichenification is limited to the flexural folds of the major joints. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the intermediate filament family.
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St John’s Laboratory Ltd.
|Product type|| |
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