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Rabbit Polyclonal Anti-MEK3 antibody (STJ98926)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-MEK3 antibody.
Check alternative names for the antibodyExpand
|AW212142 antibody|dual specificity mitogen activated protein kinase kinase 3 antibody|Dual specificity mitogen-activated protein kinase kinase 3 antibody|MAP kinase kinase 3 antibody|map2k3 antibody|MAPK ERK kinase 3 antibody|MAPK/ERK kinase 3 antibody|MAPKK 3 antibody|MAPKK3 antibody|MEK 3 antibody|MEK3 antibody|Mitogen activated protein kinase kinase 3 antibody|MKK 3 antibody|MKK3 antibody|mMKK3b antibody|MP2K3_HUMAN antibody|PRKMK 3 antibody|PRKMK3 antibody|protein kinase, mitogen-activated, kinase 3 antibody|SAPK kinase 2 antibody|SAPKK 2 antibody|SAPKK2 antibody|Stress activated protein kinase kinase 2 antibody|Anti-MEK3 antibody [EPR17345-104] (ab195037)
SCBT cat No: sc-135985|sc-81474|sc-376627|sc-271779|sc-961|sc-959|sc-136982|sc-133230|sc-137106|sc-13069|sc-136314|sc-837|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-MEK3 antibody detects endogenous MEK3 protein.
Recombinant Protein of MEK3.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-MEK3 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-MEK3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
AW212142 antibody, dual specificity mitogen activated protein kinase kinase 3 antibody, Dual specificity mitogen-activated protein kinase kinase 3 antibody, MAP kinase kinase 3 antibody, map2k3 antibody, MAPK ERK kinase 3 antibody, MAPK/ERK kinase 3 antibody, MAPKK 3 antibody, MAPKK3 antibody, MEK 3 antibody, MEK3 antibody, Mitogen activated protein kinase kinase 3 antibody, MKK 3 antibody, MKK3 antibody, mMKK3b antibody, MP2K3_HUMAN antibody, PRKMK 3 antibody, PRKMK3 antibody, protein kinase, mitogen-activated, kinase 3 antibody, SAPK kinase 2 antibody, SAPKK 2 antibody, SAPKK2 antibody, Stress activated protein kinase kinase 2 antibody
|Database links|| |
|Protein function|| |
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. .
|Protein tissue specificity|| |
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
|Involvement in disease|| |
Note=Defects in MAP2K3 may be involved in colon cancer.
|Protein sequence and domain|| |
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. ; Contains 1 protein kinase domain.
|Protein post-translational modifications|| |
Autophosphorylated. Phosphorylation on Ser-218 and Thr-222 by MAP kinase kinase kinases regulates positively the kinase activity (PubMed:8622669). Phosphorylated by TAOK2 (PubMed:11279118). .; Yersinia yopJ may acetylate Ser/Thr residues, preventing phosphorylation and activation, thus blocking the MAPK signaling pathway. .
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St John’s Laboratory Ltd.
|Product type|| |
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