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Rabbit Polyclonal Anti-MIP-3alpha antibody (STJ98775)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-MIP-3alpha antibody.
Check alternative names for the antibodyExpand
|Beta-chemokine exodus-1 antibody|C C motif chemokine ligand 20 antibody|C-C motif chemokine 20 antibody|CC chemokine LARC antibody|Ccl20 antibody|CCL20(2-70) antibody|CCL20_HUMAN antibody|Chemokine (C C motif) ligand 20 antibody|Chemokine CC motif ligand 20 antibody|CKb4 antibody|Exodus 1 antibody|Exodus antibody|LARC antibody|Liver and activation-regulated chemokine antibody|Macrophage inflammatory protein 3 alpha antibody|MIP 3 alpha antibody|MIP 3A antibody|MIP-3-alpha antibody|MIP-3a antibody|MIP3A antibody|SCYA20 antibody|Small inducible cytokine A20 antibody|Small inducible cytokine subfamily A (Cys Cys) member 20 antibody|Small-inducible cytokine A20 antibody|ST38 antibody|Anti-Macrophage Inflammatory Protein 3 alpha antibody (ab9829)
SCBT cat No: sc-9776|sc-9775|
|Catalogue No.|| |
Anti-MIP-3alpha antibody detects endogenous MIP-3alpha.
Synthetic peptide from human protein at AA range: 31-80.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-MIP-3alpha antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-MIP-3alpha antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Beta-chemokine exodus-1 antibody, C C motif chemokine ligand 20 antibody, C-C motif chemokine 20 antibody, CC chemokine LARC antibody, Ccl20 antibody, CCL20(2-70) antibody, CCL20_HUMAN antibody, Chemokine (C C motif) ligand 20 antibody, Chemokine CC motif ligand 20 antibody, CKb4 antibody, Exodus 1 antibody, Exodus antibody, LARC antibody, Liver and activation-regulated chemokine antibody, Macrophage inflammatory protein 3 alpha antibody, MIP 3 alpha antibody, MIP 3A antibody, MIP-3-alpha antibody, MIP-3a antibody, MIP3A antibody, SCYA20 antibody, Small inducible cytokine A20 antibody, Small inducible cytokine subfamily A (Cys Cys) member 20 antibody, Small-inducible cytokine A20 antibody, ST38 antibody
|Database links|| |
|Protein function|| |
Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:11352563, PubMed:11035086, PubMed:20068036). The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and various autoimmune diseases (PubMed:21376174). CCL20 acts as a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes (PubMed:9038201, PubMed:11352563). Involved in the recruitment of both the proinflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation. Required for optimal migration of thymic natural regulatory T cells (nTregs) and DN1 early thymocyte progenitor cells (By similarity). C-terminal processed forms have been shown to be equally chemotactically active for leukocytes (PubMed:11035086). Positively regulates sperm motility and chemotaxis via its binding to CCR6 which triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:23765988, PubMed:25122636). Inhibits proliferation of myeloid progenitors in colony formation assays (PubMed:9129037). May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells (By similarity). Possesses antibacterial activity towards E.coli ATCC 25922 and S.aureus ATCC 29213 (PubMed:12149255). .
|Protein tissue specificity|| |
Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level). Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon. .
|Protein sequence and domain|| |
Belongs to the intercrine beta (chemokine CC) family.
|Protein post-translational modifications|| |
C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes. .
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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