Rabbit Polyclonal Anti-Mox1 antibody (STJ98698)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-Mox1 antibody (STJ98698)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC-P, ELISA

Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-Mox1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

|GP91 2 antibody|Mitogenic oxidase (pyridine nucleotide dependent superoxide generating) antibody|Mitogenic oxidase 1 antibody|MOX-1 antibody|MOX1 antibody|NADH/NADPH mitogenic oxidase subunit P65 MOX antibody|NADH/NADPH mitogenic oxidase subunit P65-MOX antibody|NADPH oxidase 1 antibody|NADPH oxidase 1 variant NOH 1L antibody|NADPH oxidase homolog 1 antibody|NOH 1 antibody|NOH-1 antibody|NOH1 antibody|NOX-1 antibody|Nox1 antibody|NOX1_HUMAN antibody|RP1 146H21.1 antibody|Anti-NOX1 antibody (ab55831)
SCBT cat No: sc-5821|sc-25545|

Name

Anti-Mox1 antibody

Catalogue No.

STJ98698

Reactivity

Human, Mouse, Rat

Specificity

Anti-Mox1 antibody detects endogenous Mox1.

Immunogen

Synthetic peptide from human protein at AA range: 210-260.

Host

Rabbit

Applications

WB, IHC-P, ELISA

Recommended dilution

WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

65kDa

Formulation

Anti-Mox1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-Mox1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

GP91 2 antibody, Mitogenic oxidase (pyridine nucleotide dependent superoxide generating) antibody, Mitogenic oxidase 1 antibody, MOX-1 antibody, MOX1 antibody, NADH/NADPH mitogenic oxidase subunit P65 MOX antibody, NADH/NADPH mitogenic oxidase subunit P65-MOX antibody, NADPH oxidase 1 antibody, NADPH oxidase 1 variant NOH 1L antibody, NADPH oxidase homolog 1 antibody, NOH 1 antibody, NOH-1 antibody, NOH1 antibody, NOX-1 antibody, Nox1 antibody, NOX1_HUMAN antibody, RP1 146H21.1 antibody

Database links

UniProt/Swiss-Prot:Q9Y5S8

Protein function

NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.

Protein tissue specificity

NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH-1S is detected only in colon and colon carcinoma cells.

Involvement in disease

Note=Defects in NOX1 may play a role in the pathogenesis of very early onset inflammatory bowel disease (VEOIBD), a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology diagnosed before 6 years of age. VEOIBD is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but the phenotype of children with onset of Crohn disease occurring younger than the age of 10 is predominantly colonic, with a lower risk of ileal disease. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. .

Protein sequence and domain

Contains 1 FAD-binding FR-type domain. ; Contains 1 ferric oxidoreductase domain.

Protein cellular localization

Cell projection, invadopodium membrane ; Multi-pass membrane protein . Cell membrane .

Research area

All research areas>Synthesis and Degradation>Mox
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize Anti-Mox1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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