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Rabbit Polyclonal Anti-Mox1 antibody (STJ98698)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC-P, ELISA
Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Mox1 antibody.
Check alternative names for the antibodyExpand
|GP91 2 antibody|Mitogenic oxidase (pyridine nucleotide dependent superoxide generating) antibody|Mitogenic oxidase 1 antibody|MOX-1 antibody|MOX1 antibody|NADH/NADPH mitogenic oxidase subunit P65 MOX antibody|NADH/NADPH mitogenic oxidase subunit P65-MOX antibody|NADPH oxidase 1 antibody|NADPH oxidase 1 variant NOH 1L antibody|NADPH oxidase homolog 1 antibody|NOH 1 antibody|NOH-1 antibody|NOH1 antibody|NOX-1 antibody|Nox1 antibody|NOX1_HUMAN antibody|RP1 146H21.1 antibody|Anti-NOX1 antibody (ab55831)
SCBT cat No: sc-5821|sc-25545|
|Catalogue No.|| |
Human, Mouse, Rat
Anti-Mox1 antibody detects endogenous Mox1.
Synthetic peptide from human protein at AA range: 210-260.
WB, IHC-P, ELISA
|Recommended dilution|| |
WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000
|Molecular weight|| |
Anti-Mox1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-Mox1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
GP91 2 antibody, Mitogenic oxidase (pyridine nucleotide dependent superoxide generating) antibody, Mitogenic oxidase 1 antibody, MOX-1 antibody, MOX1 antibody, NADH/NADPH mitogenic oxidase subunit P65 MOX antibody, NADH/NADPH mitogenic oxidase subunit P65-MOX antibody, NADPH oxidase 1 antibody, NADPH oxidase 1 variant NOH 1L antibody, NADPH oxidase homolog 1 antibody, NOH 1 antibody, NOH-1 antibody, NOH1 antibody, NOX-1 antibody, Nox1 antibody, NOX1_HUMAN antibody, RP1 146H21.1 antibody
|Database links|| |
|Protein function|| |
NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.
|Protein tissue specificity|| |
NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH-1S is detected only in colon and colon carcinoma cells.
|Involvement in disease|| |
Note=Defects in NOX1 may play a role in the pathogenesis of very early onset inflammatory bowel disease (VEOIBD), a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology diagnosed before 6 years of age. VEOIBD is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may affect any part of the gastrointestinal tract from the mouth to the anus, but the phenotype of children with onset of Crohn disease occurring younger than the age of 10 is predominantly colonic, with a lower risk of ileal disease. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. .
|Protein sequence and domain|| |
Contains 1 FAD-binding FR-type domain. ; Contains 1 ferric oxidoreductase domain.
|Protein cellular localization|| |
Cell projection, invadopodium membrane ; Multi-pass membrane protein . Cell membrane .
AntibodyPlus can customize Anti-Mox1 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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