Rabbit Polyclonal Anti-PACAP antibody (STJ98819)

$99.00$319.00

Reactivity: Human
Applications: IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-PACAP antibody (STJ98819)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC-P, ELISA

Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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SCBT cat No: sc-168603|sc-168605|

Name

Anti-PACAP antibody

Catalogue No.

STJ98819

Reactivity

Human

Specificity

Anti-PACAP antibody detects endogenous PACAP.

Immunogen

Synthetic peptide from human protein at AA range: 1-50.

Host

Rabbit

Applications

IHC-P, ELISA

Recommended dilution

IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-PACAP antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-PACAP antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

MZB1 antibody, Caspase 2 binding protein antibody, FLJ32987 antibody, HSPC190 antibody, Marginal zone B and B1 cell specific protein antibody, MEDA 7 antibody, Mesenteric estrogen dependent adipose 7 antibody, Mesenteric oestrogen dependent adipose gene 7 antibody, MGC29506 antibody, PACAP antibody, pERp1 antibody, Plasma cell-induced ER protein 1 antibody, Plasma cell-induced resident endoplasmic reticulum protein antibody, Plasma cell-induced resident ER protein antibody, Proapoptotic caspase adapter protein antibody

Database links

UniProt/Swiss-Prot:Q8WU39

Protein function

Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. .; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.

Protein tissue specificity

Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat. .

Protein sequence and domain

Belongs to the MZB1 family.

Protein post-translational modifications

Forms an interchain disulfide bond with IgM monomers. .

Protein cellular localization

Isoform 1: Endoplasmic reticulum lumen . Secreted .; Isoform 2: Cytoplasm . Note=Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957).

Note

AntibodyPlus can customize Anti-PACAP antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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