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Rabbit Polyclonal Anti-PACAP antibody (STJ98819)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-PACAP antibody.
Check alternative names for the antibodyExpand
|MZB1 antibody|Caspase 2 binding protein antibody|FLJ32987 antibody|HSPC190 antibody|Marginal zone B and B1 cell specific protein antibody|MEDA 7 antibody|Mesenteric estrogen dependent adipose 7 antibody|Mesenteric oestrogen dependent adipose gene 7 antibody|MGC29506 antibody|PACAP antibody|pERp1 antibody|Plasma cell-induced ER protein 1 antibody|Plasma cell-induced resident endoplasmic reticulum protein antibody|Plasma cell-induced resident ER protein antibody|Proapoptotic caspase adapter protein antibody|Anti-Proapoptotic Caspase Adaptor Protein antibody [EPR11544] (ab181205)
SCBT cat No: sc-168603|sc-168605|
|Catalogue No.|| |
Anti-PACAP antibody detects endogenous PACAP.
Synthetic peptide from human protein at AA range: 1-50.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-PACAP antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-PACAP antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
MZB1 antibody, Caspase 2 binding protein antibody, FLJ32987 antibody, HSPC190 antibody, Marginal zone B and B1 cell specific protein antibody, MEDA 7 antibody, Mesenteric estrogen dependent adipose 7 antibody, Mesenteric oestrogen dependent adipose gene 7 antibody, MGC29506 antibody, PACAP antibody, pERp1 antibody, Plasma cell-induced ER protein 1 antibody, Plasma cell-induced resident endoplasmic reticulum protein antibody, Plasma cell-induced resident ER protein antibody, Proapoptotic caspase adapter protein antibody
|Database links|| |
|Protein function|| |
Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. .; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
|Protein tissue specificity|| |
Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat. .
|Protein sequence and domain|| |
Belongs to the MZB1 family.
|Protein post-translational modifications|| |
Forms an interchain disulfide bond with IgM monomers. .
|Protein cellular localization|| |
Isoform 1: Endoplasmic reticulum lumen . Secreted .; Isoform 2: Cytoplasm . Note=Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957).
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St John’s Laboratory Ltd.
|Product type|| |
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