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Rabbit Polyclonal Anti-Parathyroid hormone/parathyroid hormone-related peptide receptor antibody (STJ98966)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Parathyroid hormone/parathyroid hormone-related peptide receptor antibody.
Check alternative names for the antibodyExpand
|MGC138426 antibody|PTH receptor antibody|PTH/PTHr receptor antibody|PTH/PTHrP receptor antibody|PTH/PTHrP type I receptor antibody|PTH1 receptor antibody|PTH1R antibody|PTH1R_HUMAN antibody|PTHR 1 antibody|PTHR antibody|PTHR1 antibody|Anti-Parathyroid Hormone Receptor 1 antibody (ab75150)
SCBT cat No: sc-12722|sc-12777|sc-20749|
Anti-Parathyroid hormone/parathyroid hormone-related peptide receptor antibody
|Catalogue No.|| |
Anti-Parathyroid hormone/parathyroid hormone-related peptide receptor antibody detects endogenous Parathyroid hormone/parathyroid hormone-related peptide receptor.
Synthetic peptide from human protein at AA range: 46-122.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Parathyroid hormone/parathyroid hormone-related peptide receptor antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Parathyroid hormone/parathyroid hormone-related peptide receptor antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
MGC138426 antibody, PTH receptor antibody, PTH/PTHr receptor antibody, PTH/PTHrP receptor antibody, PTH/PTHrP type I receptor antibody, PTH1 receptor antibody, PTH1R antibody, PTH1R_HUMAN antibody, PTHR 1 antibody, PTHR antibody, PTHR1 antibody
|Database links|| |
|Protein function|| |
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. .
|Protein tissue specificity|| |
Expressed in most tissues. Most abundant in kidney, bone and liver. .
|Involvement in disease|| |
Jansen metaphyseal chondrodysplasia (JMC) [MIM:156400]: Rare autosomal dominant disorder characterized by a short-limbed dwarfism associated with hypercalcemia and normal or low serum concentrations of the two parathyroid hormones. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Chondrodysplasia Blomstrand type (BOCD) [MIM:215045]: Severe skeletal dysplasia. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Enchondromatosis multiple (ENCHOM) [MIM:166000]: A condition characterized by multiple formation of enchondromas, benign neoplasms derived from mesodermal cells that form cartilage. Enchondromas remain within the substance of a cartilage or bone. Clinical problems caused by enchondromas include skeletal deformity and the potential for malignant change to osteosarcoma. . Note=The disease may be caused by mutations affecting the gene represented in this entry.; Eiken skeletal dysplasia (EISD) [MIM:600002]: A rare skeletal dysplasia characterized by severely retarded ossification, principally of the epiphyses, pelvis, hands and feet, as well as by abnormal modeling of the bones in hands and feet, abnormal persistence of cartilage in the pelvis and mild growth retardation. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Primary failure of tooth eruption (PFE) [MIM:125350]: Rare condition that has high penetrance and variable expressivity and in which tooth retention occurs without evidence of any obvious mechanical interference. Instead, malfunction of the eruptive mechanism itself appears to cause nonankylosed permanent teeth to fail to erupt, although the eruption pathway has been cleared by bone resorption. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the G-protein coupled receptor 2 family.
|Protein cellular localization|| |
Cell membrane ; Multi-pass membrane protein .
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St John’s Laboratory Ltd.
|Product type|| |
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