Rabbit Polyclonal Anti-PBEF antibody (STJ99328)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-PBEF antibody (STJ99328)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

|1110035O14Rik antibody|AI314458 antibody|AI480535 antibody|DKFZP666B131 antibody|EC 2.4.2.12 antibody|MGC117256 antibody|NAmPRTase antibody|Nampt antibody|NAMPT_HUMAN antibody|Nicotinamide phosphoribosyltransferase antibody|PBEF 1 antibody|PBEF antibody|PBEF1 antibody|Pre B cell colony enhancing factor 1 antibody|Pre B cell colony enhancing factor antibody|Pre B cell enhancing factor antibody|Pre-B cell-enhancing factor antibody|Pre-B-cell colony-enhancing factor 1 antibody|VF antibody|Visfatin antibody|Anti-Visfatin antibody (ab45890)
SCBT cat No: sc-130058|sc-46440|sc-166866|sc-393444|sc-393443|sc-393510|sc-166946|sc-67020|

Size

20ul trial, 50ul, 100ul, 200ul

Name

Anti-PBEF antibody

Catalogue No.

STJ99328

Reactivity

Human, Mouse, Rat

Specificity

Anti-PBEF antibody detects endogenous levels of PBEF.

Immunogen

Synthesized peptide derived from human PBEF. at AA range: 411-460.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

54kDa

Formulation

Anti-PBEF antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-PBEF antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

1110035O14Rik antibody, AI314458 antibody, AI480535 antibody, DKFZP666B131 antibody, EC 2.4.2.12 antibody, MGC117256 antibody, NAmPRTase antibody, Nampt antibody, NAMPT_HUMAN antibody, Nicotinamide phosphoribosyltransferase antibody, PBEF 1 antibody, PBEF antibody, PBEF1 antibody, Pre B cell colony enhancing factor 1 antibody, Pre B cell colony enhancing factor antibody, Pre B cell enhancing factor antibody, Pre-B cell-enhancing factor antibody, Pre-B-cell colony-enhancing factor 1 antibody, VF antibody, Visfatin antibody

Database links

UniProt/Swiss-Prot:P43490

Protein function

Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity). .

Protein tissue specificity

Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.

Protein sequence and domain

Belongs to the NAPRTase family.

Protein cellular localization

Nucleus . Cytoplasm . Secreted . Note=Under non-inflammatory conditions, visfatin predominantly exhibits a granular pattern within the nucleus. Secreted by endothelial cells upon IL-1beta stimulation. Abundantly secreted in milk, reaching 100-fold higher concentrations compared to maternal serum. .

Research area

All research areas>Lymphocyte Signaling>PBEF
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize Anti-PBEF antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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