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Rabbit Polyclonal Anti-PBEF antibody (STJ99328)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-PBEF antibody.
Check alternative names for the antibodyExpand
|1110035O14Rik antibody|AI314458 antibody|AI480535 antibody|DKFZP666B131 antibody|EC 22.214.171.124 antibody|MGC117256 antibody|NAmPRTase antibody|Nampt antibody|NAMPT_HUMAN antibody|Nicotinamide phosphoribosyltransferase antibody|PBEF 1 antibody|PBEF antibody|PBEF1 antibody|Pre B cell colony enhancing factor 1 antibody|Pre B cell colony enhancing factor antibody|Pre B cell enhancing factor antibody|Pre-B cell-enhancing factor antibody|Pre-B-cell colony-enhancing factor 1 antibody|VF antibody|Visfatin antibody|Anti-Visfatin antibody (ab45890)
SCBT cat No: sc-130058|sc-46440|sc-166866|sc-393444|sc-393443|sc-393510|sc-166946|sc-67020|
20ul trial, 50ul, 100ul, 200ul
|Catalogue No.|| |
Human, Mouse, Rat
Anti-PBEF antibody detects endogenous levels of PBEF.
Synthesized peptide derived from human PBEF. at AA range: 411-460.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-PBEF antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-PBEF antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
1110035O14Rik antibody, AI314458 antibody, AI480535 antibody, DKFZP666B131 antibody, EC 126.96.36.199 antibody, MGC117256 antibody, NAmPRTase antibody, Nampt antibody, NAMPT_HUMAN antibody, Nicotinamide phosphoribosyltransferase antibody, PBEF 1 antibody, PBEF antibody, PBEF1 antibody, Pre B cell colony enhancing factor 1 antibody, Pre B cell colony enhancing factor antibody, Pre B cell enhancing factor antibody, Pre-B cell-enhancing factor antibody, Pre-B-cell colony-enhancing factor 1 antibody, VF antibody, Visfatin antibody
|Database links|| |
|Protein function|| |
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity). .
|Protein tissue specificity|| |
Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.
|Protein sequence and domain|| |
Belongs to the NAPRTase family.
|Protein cellular localization|| |
Nucleus . Cytoplasm . Secreted . Note=Under non-inflammatory conditions, visfatin predominantly exhibits a granular pattern within the nucleus. Secreted by endothelial cells upon IL-1beta stimulation. Abundantly secreted in milk, reaching 100-fold higher concentrations compared to maternal serum. .
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St John’s Laboratory Ltd.
|Product type|| |
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