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Rabbit Polyclonal Anti-PON1 antibody (STJ98804)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC-P, ELISA
Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-PON1 antibody.
Check alternative names for the antibodyExpand
|A esterase 1 antibody|A-esterase 1 antibody|Aromatic esterase 1 antibody|Arylesterase 1 antibody|Arylesterase B type antibody|ESA antibody|Esterase A antibody|K 45 antibody|K-45 antibody|MVCD5 antibody|Paraoxonase 1 antibody|Paraoxonase antibody|Paraoxonase B type antibody|Paraoxonase, plasma antibody|Paraoxonase1 antibody|PON 1 antibody|PON antibody|PON1 antibody|PON1_HUMAN antibody|Serum aryldiakylphosphatase antibody|Serum aryldialkylphosphatase 1 antibody|Serum paraoxonase/arylesterase 1 antibody|Anti-PON1 antibody [17A12] (ab24261)
SCBT cat No: sc-59646|sc-25791|
|Catalogue No.|| |
Anti-PON1 antibody detects endogenous PON1.
Synthetic peptide from human protein at AA range: 51-100.
|Recommended dilution|| |
IHC-P 1:50-300; ELISA 1:5000-20000
Anti-PON1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Anti-PON1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
A esterase 1 antibody, A-esterase 1 antibody, Aromatic esterase 1 antibody, Arylesterase 1 antibody, Arylesterase B type antibody, ESA antibody, Esterase A antibody, K 45 antibody, K-45 antibody, MVCD5 antibody, Paraoxonase 1 antibody, Paraoxonase antibody, Paraoxonase B type antibody, Paraoxonase, plasma antibody, Paraoxonase1 antibody, PON 1 antibody, PON antibody, PON1 antibody, PON1_HUMAN antibody, Serum aryldiakylphosphatase antibody, Serum aryldialkylphosphatase 1 antibody, Serum paraoxonase/arylesterase 1 antibody
|Database links|| |
|Protein function|| |
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. .
|Protein tissue specificity|| |
Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. .
|Involvement in disease|| |
Microvascular complications of diabetes 5 (MVCD5) [MIM:612633]: Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Homozygosity for the Leu-55 allele is strongly associated with the development of retinal disease in diabetic patients.
|Protein sequence and domain|| |
Belongs to the paraoxonase family.
|Protein post-translational modifications|| |
Glycosylated. .; The signal sequence is not cleaved.; Present in two forms, form B contains a disulfide bond, form A does not.
|Protein cellular localization|| |
Secreted, extracellular space.
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St John’s Laboratory Ltd.
|Product type|| |
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