Rabbit Polyclonal Anti-PON1 antibody (STJ98804)

$99.00$319.00

Reactivity: Human
Applications: IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-PON1 antibody (STJ98804)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IHC-P, ELISA

Recommended dilution: IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Anti-PON1 antibody.

Alternative names:

Check alternative names for the antibody

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|A esterase 1 antibody|A-esterase 1 antibody|Aromatic esterase 1 antibody|Arylesterase 1 antibody|Arylesterase B type antibody|ESA antibody|Esterase A antibody|K 45 antibody|K-45 antibody|MVCD5 antibody|Paraoxonase 1 antibody|Paraoxonase antibody|Paraoxonase B type antibody|Paraoxonase, plasma antibody|Paraoxonase1 antibody|PON 1 antibody|PON antibody|PON1 antibody|PON1_HUMAN antibody|Serum aryldiakylphosphatase antibody|Serum aryldialkylphosphatase 1 antibody|Serum paraoxonase/arylesterase 1 antibody|Anti-PON1 antibody [17A12] (ab24261)
SCBT cat No: sc-59646|sc-25791|

Name

Anti-PON1 antibody

Catalogue No.

STJ98804

Reactivity

Human

Specificity

Anti-PON1 antibody detects endogenous PON1.

Immunogen

Synthetic peptide from human protein at AA range: 51-100.

Host

Rabbit

Applications

IHC-P, ELISA

Recommended dilution

IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

Anti-PON1 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-PON1 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

A esterase 1 antibody, A-esterase 1 antibody, Aromatic esterase 1 antibody, Arylesterase 1 antibody, Arylesterase B type antibody, ESA antibody, Esterase A antibody, K 45 antibody, K-45 antibody, MVCD5 antibody, Paraoxonase 1 antibody, Paraoxonase antibody, Paraoxonase B type antibody, Paraoxonase, plasma antibody, Paraoxonase1 antibody, PON 1 antibody, PON antibody, PON1 antibody, PON1_HUMAN antibody, Serum aryldiakylphosphatase antibody, Serum aryldialkylphosphatase 1 antibody, Serum paraoxonase/arylesterase 1 antibody

Database links

UniProt/Swiss-Prot:P27169

Protein function

Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. .

Protein tissue specificity

Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. .

Involvement in disease

Microvascular complications of diabetes 5 (MVCD5) [MIM:612633]: Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Homozygosity for the Leu-55 allele is strongly associated with the development of retinal disease in diabetic patients.

Protein sequence and domain

Belongs to the paraoxonase family.

Protein post-translational modifications

Glycosylated. .; The signal sequence is not cleaved.; Present in two forms, form B contains a disulfide bond, form A does not.

Protein cellular localization

Secreted, extracellular space.

Note

AntibodyPlus can customize Anti-PON1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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