Rabbit Polyclonal Anti-SOCS-2 antibody (STJ98710)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-SOCS-2 antibody (STJ98710)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC-P, ELISA

Recommended dilution: WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|CIS 2 antibody|CIS-2 antibody|CIS2 antibody|Cish 2 antibody|Cish2 antibody|Cytokine inducible SH2 protein 2 antibody|Cytokine-inducible SH2 protein 2 antibody|SOCS 2 antibody|SOCS-2 antibody|Socs2 antibody|SOCS2_HUMAN antibody|SSI 2 antibody|SSI-2 antibody|SSI2 antibody|STAT induced STAT inhibitor 2 antibody|STAT-induced STAT inhibitor 2 antibody|STATI 2 antibody|STATI2 antibody|Suppressor of cytokine signaling 2 antibody|Anti-SOCS2 antibody (ab3692)
SCBT cat No:

Name

Anti-SOCS-2 antibody

Catalogue No.

STJ98710

Reactivity

Human, Mouse, Rat

Specificity

Anti-SOCS-2 antibody detects endogenous SOCS-2.

Immunogen

Synthetic peptide from human protein at AA range: 120-170.

Host

Rabbit

Applications

WB, IHC-P, ELISA

Recommended dilution

WB 1:500-2000; IHC-P 1:50-300; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

35kDa

Formulation

Anti-SOCS-2 antibody was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-SOCS-2 antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

CIS 2 antibody, CIS-2 antibody, CIS2 antibody, Cish 2 antibody, Cish2 antibody, Cytokine inducible SH2 protein 2 antibody, Cytokine-inducible SH2 protein 2 antibody, SOCS 2 antibody, SOCS-2 antibody, Socs2 antibody, SOCS2_HUMAN antibody, SSI 2 antibody, SSI-2 antibody, SSI2 antibody, STAT induced STAT inhibitor 2 antibody, STAT-induced STAT inhibitor 2 antibody, STATI 2 antibody, STATI2 antibody, Suppressor of cytokine signaling 2 antibody

Database links

UniProt/Swiss-Prot:O14508

Protein function

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein tissue specificity

High expression in heart, placenta, lung, kidney and prostate.

Protein sequence and domain

Contains 1 SH2 domain. ; Contains 1 SOCS box domain. The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.

Research area

All research areas>Signaling Intermediates>SOCS
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Anti-SOCS-2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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