Rabbit Polyclonal Anti-Sodium Potassium ATPase alpha-1 antibody (Phospho-Tyr260) (STJ98679)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Anti-Sodium Potassium ATPase alpha-1 antibody (Phospho-Tyr260) (STJ98679)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:5000-20000

Recommended protocols: check protocols

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SCBT cat No:

Name

Anti-Sodium Potassium ATPase alpha-1 antibody (Phospho-Tyr260)

Catalogue No.

STJ98679

Reactivity

Human, Mouse, Rat

Specificity

Anti-Sodium Potassium ATPase alpha-1 antibody (Phospho-Tyr260) detects endogenous Sodium Potassium ATPase alpha-1 when Phospho occurs at Tyr260).

Immunogen

Synthetic peptide from human protein at AA range: 230-290.

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:5000-20000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

115kDa

Formulation

Anti-Sodium Potassium ATPase alpha-1 antibody (Phospho-Tyr260) was tube-contained in PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Concentration

1 mg/ml

Purification

Anti-Sodium Potassium ATPase alpha-1 antibody (Phospho-Tyr260) was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Database links

UniProt/Swiss-Prot:P05023

Protein function

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Protein sequence and domain

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.

Protein post-translational modifications

Phosphorylation on Tyr-10 modulates pumping activity. Phosphorylation of Ser-943 by PKA modulates the response of ATP1A1 to PKC. Dephosphorylation by protein phosphatase 2A (PP2A) following increases in intracellular sodium, leading to increase catalytic activity (By similarity). .

Protein cellular localization

Cell membrane ; Multi-pass membrane protein . Melanosome . Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .

Note

AntibodyPlus can customize Anti-Sodium Potassium ATPase alpha-1 antibody (Phospho-Tyr260) according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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